The role of vasoactive intestinal peptide in pulmonary diseases

HL Zhong, PZ Li, D Li, CX Guan, Y Zhou - Life Sciences, 2023 - Elsevier
Vasoactive intestinal peptide (VIP) is an abundant neurotransmitter in the lungs and other
organs. Its discovery dates back to 1970. And VIP gains attention again due to the potential …

[HTML][HTML] Vasoactive intestinal peptide inhaled agonists: potential role in respiratory therapeutics

AG Mathioudakis, V Chatzimavridou-Grigoriadou… - Hippokratia, 2013 - ncbi.nlm.nih.gov
Abstract Purpose of review: Vasoactive Intestinal Peptide (VIP) is a neuropeptide, expressed
by lymphoid as well as neural cells, which has diverse effects on the cellular mediators of …

Prospect of vasoactive intestinal peptide therapy for COPD/PAH and asthma: a review

D Wu, D Lee, YK Sung - Respiratory research, 2011 - Springer
There is mounting evidence that pulmonary arterial hypertension (PAH), asthma and chronic
obstructive pulmonary disease (COPD) share important pathological features, including …

Novel concepts of neuropeptide-based drug therapy: vasoactive intestinal polypeptide and its receptors

DA Groneberg, KF Rabe, A Fischer - European journal of pharmacology, 2006 - Elsevier
Chronic inflammatory airway diseases such as bronchial asthma or chronic obstructive
pulmonary disease (COPD) are major contributors to the global burden of disease. Although …

Vasodilatory effect of the stable vasoactive intestinal peptide analog RO 25-1553 in murine and rat lungs

J Yin, L Wang, N Yin, A Tabuchi, H Kuppe, G Wolff… - PloS one, 2013 - journals.plos.org
Rationale Stable analogs of vasoactive intestinal peptide (VIP) have been proposed as
novel line of therapy in chronic obstructive pulmonary disease (COPD) based on their …

Vasoactive intestinal peptide

SI Said - Airways smooth muscle: peptide receptors, ion …, 1995 - Springer
VIP was first isolated from the small intestine, but it had been discovered earlier in the lung,
as a vasodilator peptide [1, 2]. Several years later it was identified in the central and …

Vasoactive intestinal peptide (VIP) receptor expression in monocyte-derived macrophages from COPD patients

B Burian, A Storka, BA Marzluf, YC Yen, C Lambers… - Peptides, 2010 - Elsevier
Vasoactive intestinal peptide (VIP) is one of the most abundant molecules found in the
respiratory tract. Due to its anti-inflammatory and bronchodilatatory properties, it has been …

Vasoactive intestinal polypeptide as mediator of asthma

DA Groneberg, J Springer, A Fischer - Pulmonary pharmacology & …, 2001 - Elsevier
Vasoactive intestinal polypeptide (VIP) is one of the most abundant, biologically active
peptides found in the human lung. VIP is a likely neurotransmitter or neuromodulator of the …

Vasoactive intestinal polypeptide in the respiratory tract

SI Said - Neuropeptides in respiratory medicine, 2017 - taylorfrancis.com
As a neuropeptide with wide distribution, vasoactive intestinal polypeptide (VIP) is a likely
neurotransmitter or neuromodulator. Though first isolated from small intestine, VIP had …

The vasoactive intestinal peptide receptor turnover in pulmonary arteries indicates an important role for VIP in the rat lung circulation

V Petkov, T Gentscheva, C Schamberger… - Annals of the New …, 2006 - Wiley Online Library
Vasoactive intestinal peptide (VIP) is a potent vasorelaxing peptide that plays a role in lung
physiology and possibly in pulmonary hypertension. We investigated the turnover of the VIP …