Prevention of Alzheimer's disease: Omega-3 fatty acid and phenolic anti-oxidant interventions
Alzheimer's disease (AD) and cardiovascular disease (CVD) are syndromes of aging that
share analogous lesions and risk factors, involving lipoproteins, oxidative damage and …
share analogous lesions and risk factors, involving lipoproteins, oxidative damage and …
Docosahexaenoic acid protects from amyloid and dendritic pathology in an Alzheimer's disease mouse model
GM Cole, SA Frautschy - Nutrition and health, 2006 - journals.sagepub.com
Genetic data argues that Alzheimer's disease (AD) can be initiated by aggregates of a 42
amino acid beta amyloid peptide (Aβ42). The Aβ aggregates, notably small oligomer …
amino acid beta amyloid peptide (Aβ42). The Aβ aggregates, notably small oligomer …
Dietary fatty acids and the aging brain
GM Cole, QL Ma, SA Frautschy - Nutrition reviews, 2010 - academic.oup.com
Aging contributes to physiological decline and vulnerability to disease. In the brain, even
with minimal neuronal loss, aging increases oxidative damage, inflammation, demyelination …
with minimal neuronal loss, aging increases oxidative damage, inflammation, demyelination …
Omega-3 fatty acids and dementia
GM Cole, QL Ma, SA Frautschy - Prostaglandins, Leukotrienes and …, 2009 - Elsevier
More than a dozen epidemiological studies have reported that reduced levels or intake of
omega-3 fatty acids or fish consumption is associated with increased risk for age-related …
omega-3 fatty acids or fish consumption is associated with increased risk for age-related …
Why pleiotropic interventions are needed for Alzheimer's disease
SA Frautschy, GM Cole - Molecular neurobiology, 2010 - Springer
Alzheimer's disease (AD) involves a complex pathological cascade thought to be initially
triggered by the accumulation of β-amyloid (Aβ) peptide aggregates or aberrant amyloid …
triggered by the accumulation of β-amyloid (Aβ) peptide aggregates or aberrant amyloid …
A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model
Epidemiological studies suggest that increased intake of the omega-3 (n-3) polyunsaturated
fatty acid (PUFA) docosahexaenoic acid (DHA) is associated with reduced risk of …
fatty acid (PUFA) docosahexaenoic acid (DHA) is associated with reduced risk of …
Omega‐3 Fatty Acids in Early Prevention of Inflammatory Neurodegenerative Disease: A Focus on Alzheimer's Disease
J Thomas, CJ Thomas, J Radcliffe… - BioMed research …, 2015 - Wiley Online Library
Alzheimer's disease (AD) is the leading cause of dementia and the most common
neurodegenerative disease in the elderly. Furthermore, AD has provided the most positive …
neurodegenerative disease in the elderly. Furthermore, AD has provided the most positive …
Neuroprotective action of omega-3 polyunsaturated fatty acids against neurodegenerative diseases: evidence from animal studies
Studies in animals clearly show that oral intake of docosahexaenoic acid (DHA) can alter
brain DHA concentrations and thereby modify brain functions. This provides us with an …
brain DHA concentrations and thereby modify brain functions. This provides us with an …
Omega-3 fatty acids: potential role in the management of early Alzheimer's disease
GA Jicha, WR Markesbery - Clinical interventions in aging, 2010 - Taylor & Francis
Omega-3 fatty acids are essential for brain growth and development. They play an important
role throughout life, as critical modulators of neuronal function and regulation of oxidative …
role throughout life, as critical modulators of neuronal function and regulation of oxidative …
Alzheimer's disease, amnestic mild cognitive impairment, and age-associated memory impairment: current understanding and progress toward integrative prevention.
PM Kidd - Alternative Medicine Review, 2008 - search.ebscohost.com
Alzheimer's disease (AD) is the most common form of dementia. AD initially targets memory
and progressively destroys the mind. The brain atrophies as the neocortex suffers neuronal …
and progressively destroys the mind. The brain atrophies as the neocortex suffers neuronal …
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