MicroRNAs and their big therapeutic impacts: delivery strategies for cancer intervention
C Holjencin, A Jakymiw - Cells, 2022 - mdpi.com
Three decades have passed from the initial discovery of a microRNA (miRNA) in
Caenorhabditis elegans to our current understanding that miRNAs play essential roles in …
Caenorhabditis elegans to our current understanding that miRNAs play essential roles in …
A comprehensive review of cancer MicroRNA therapeutic delivery strategies
A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
In the field of molecular oncology, microRNAs (miRNAs) and their role in regulating
physiological processes and cancer pathogenesis have been a revolutionary discovery over …
physiological processes and cancer pathogenesis have been a revolutionary discovery over …
MicroRNAs as new therapeutic targets and tools in cancer
P Gandellini, V Profumo, M Folini… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: MicroRNAs (miRNAs) are a class of endogenous, non-coding small RNAs that
negatively regulate gene expression at the post-transcriptional level. Several studies have …
negatively regulate gene expression at the post-transcriptional level. Several studies have …
MicroRNAs as therapeutic targets and their potential applications in cancer therapy
WCS Cho - Expert opinion on therapeutic targets, 2012 - Taylor & Francis
Introduction: The results of cancer-associated miRNA research have yielded surprising
insights into the pathogenesis of a range of different cancers. Many of the dysregulated …
insights into the pathogenesis of a range of different cancers. Many of the dysregulated …
Exploiting the therapeutic potential of microRNAs in human cancer
WCS Cho - Expert opinion on therapeutic targets, 2012 - Taylor & Francis
Dysregulation of microRNAs (miRNAs) has been widely shown to be associated with the
development and progression of cancer. Recent studies discovered a handful of miRNAs …
development and progression of cancer. Recent studies discovered a handful of miRNAs …
MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
R Rupaimoole, FJ Slack - Nature reviews Drug discovery, 2017 - nature.com
In just over two decades since the discovery of the first microRNA (miRNA), the field of
miRNA biology has expanded considerably. Insights into the roles of miRNAs in …
miRNA biology has expanded considerably. Insights into the roles of miRNAs in …
[HTML][HTML] Modulating microRNAs in cancer: Next-generation therapies
N Arghiani, K Shah - Cancer Biology & Medicine, 2022 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are a class of endogenously expressed non-coding regulators of the
genome with an ability to mediate a variety of biological and pathological processes. There …
genome with an ability to mediate a variety of biological and pathological processes. There …
MicroRNAs in cancer therapeutics: “from the bench to the bedside”
PC Monroig-Bosque, CA Rivera… - Expert opinion on …, 2015 - Taylor & Francis
MicroRNAs (miRNAs) are non-coding RNA transcripts that regulate physiological processes
by targeting proteins directly. Their involvement in research has been robust, and evidence …
by targeting proteins directly. Their involvement in research has been robust, and evidence …
The road toward microRNA therapeutics
AG Seto - The international journal of biochemistry & cell biology, 2010 - Elsevier
Within the last 15 years, microRNAs (miRNAs) have emerged as powerful regulators of gene
expression. Highly conserved, these small RNAs appear to regulate nearly every aspect of …
expression. Highly conserved, these small RNAs appear to regulate nearly every aspect of …