Therapeutic gene editing is becoming more feasible with the emergence of the Clustered
Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein …

Background The clustered regularly interspaced short palindromic repeats (CRISPR) and
Cas9 protein system is a revolutionary tool for gene therapy. Despite promising reports of …

The CRISPR-Cas9 system is a powerful gene-editing tool with wide-ranging applications,
but the safe and efficient intracellular delivery of CRISPR components remains a challenge …

A facile method was designed that can specifically deliver CRISPR/Cas9 into target cells
nuclei and reduce the off-target effects. A multifunctional delivery vector for FOXM1 knockout …

Emerging clustered regularly interspaced short palindromic repeat/associated protein
(CRISPR/Cas) genome editing technology shows great potential in gene therapy. However …

Programmable endonucleases such as CRISPR/Cas9 system emerge as a promising tool to
treat genetic and non-genetic diseases such as hypercholesterolemia, Duchenne muscular …

CRISPR/Cas system has become one of the most powerful techologies in biomedical
research, and has showed great potentials in the gene related diseases. However, efficient …

CRISPR–Cas9 is a revolutionary genome-editing technology that has enormous potential
for the treatment of genetic diseases. However, the lack of efficient and safe, non-viral …

Delivery of CRISPR (clustered regularly interspaced short palindromic repeats)/CRISPR‐
associated protein‐9 (Cas9) represents a major hurdle for successful clinical translation of …

The CRISPR-Cas9 system is an emerging therapeutic tool with the potential to correct
diverse genetic disorders. However, for gene therapy applications, an efficient delivery …