Knockdown of the cAMP‐dependent protein kinase (PKA) Type Iα regulatory subunit in mouse oocytes disrupts meiotic arrest and results in meiotic spindle defects
FE Duncan, SB Moss, CJ Williams - Developmental dynamics, 2006 - Wiley Online Library
In mammalian oocytes, cyclic AMP‐dependent protein kinase (PKA) is responsible for
maintaining meiotic arrest. We examined the role of the predominant regulatory subunit, RIα …
maintaining meiotic arrest. We examined the role of the predominant regulatory subunit, RIα …
A-kinase anchor proteins as potential regulators of protein kinase A function in oocytes
RL Brown, T Ord, SB Moss… - Biology of …, 2002 - academic.oup.com
In the mammalian oocyte, the cAMP-dependent protein kinase (PKA) has critical functions in
the maintenance of meiotic arrest and oocyte maturation. Because PKA is spatially …
the maintenance of meiotic arrest and oocyte maturation. Because PKA is spatially …
An active protein kinase A (PKA) is involved in meiotic arrest of rat growing oocytes
M Kovo, M Kandli-Cohen, M Ben-Haim… - …, 2006 - rep.bioscientifica.com
Reinitiation of meiosis in meiotically competent, fully grown mammalian oocytes is governed
by a fall in intraoocyte cAMP concentrations and the subsequent inactivation of protein …
by a fall in intraoocyte cAMP concentrations and the subsequent inactivation of protein …
Protein Kinase A (PKA)-Restrictcive and PKA-Permissive Phases of Oocyte Maturation
J Wang, WL Cao, XJ Liu - Cell cycle, 2006 - Taylor & Francis
Substantial evidence has indicated that cAMP-dependent protein kinase (protein kinase A
orPKA) plays a critical role in maintaining meiotic prophase arrest in vertebrate oocytes …
orPKA) plays a critical role in maintaining meiotic prophase arrest in vertebrate oocytes …
Expression and modification of PKA and AKAPs during meiosis in rat oocytes
M Kovo, RV Schillace, D Galiani, LB Josefsberg… - Molecular and cellular …, 2002 - Elsevier
Meiosis in oocytes is initiated during fetal life, arrested around birth and resumed after
puberty. Meiotic arrest is controlled by a cAMP-dependent protein kinase (PKA)-mediated …
puberty. Meiotic arrest is controlled by a cAMP-dependent protein kinase (PKA)-mediated …
Regulation of the G2/M transition in Xenopus oocytes by the cAMP-dependent protein kinase
Vertebrate oocytes are arrested in G 2 phase of the cell cycle at the prophase border of
meiosis I. Progesterone treatment of Xenopus oocytes releases the G 2 block and promotes …
meiosis I. Progesterone treatment of Xenopus oocytes releases the G 2 block and promotes …
Evidence that protein kinase C (PKC) participates in the meiosis I to meiosis II transition in mouse oocytes
MM Viveiros, Y Hirao, JJ Eppig - Developmental Biology, 2001 - Elsevier
Oocytes from LTXBO mice exhibit a delayed entry into anaphase I and frequently enter
interphase after the first meiotic division. This unique oocyte model was used to test the …
interphase after the first meiotic division. This unique oocyte model was used to test the …
Inhibition of Xenopus oocyte meiotic maturation by catalytically inactive protein kinase A
A Schmitt, AR Nebreda - Proceedings of the National …, 2002 - National Acad Sciences
Progesterone induces G2-arrested Xenopus oocytes to develop into fertilizable eggs in a
process called meiotic maturation. Protein kinase A (PKA), the cAMP-dependent protein …
process called meiotic maturation. Protein kinase A (PKA), the cAMP-dependent protein …
Suppression of chemically induced and spontaneous mouse oocyte activation by AMP-activated protein kinase
R Ya, SM Downs - Biology of reproduction, 2013 - academic.oup.com
Oocyte activation is an important process triggered by fertilization that initiates embryonic
development. However, parthenogenetic activation can occur either spontaneously or with …
development. However, parthenogenetic activation can occur either spontaneously or with …
Involvement of cAMP-dependent protein kinase and protein phosphorylation in regulation of mouse oocyte maturation
EA Bornslaeger, P Mattei, RM Schultz - Developmental biology, 1986 - Elsevier
We report the results of experiments which support the hypothesis that, in mouse oocytes, a
decrease in intraoocyte cyclic AMP (cAMP) initiates meiotic maturation; oocytes …
decrease in intraoocyte cyclic AMP (cAMP) initiates meiotic maturation; oocytes …