Estrogen receptors (ERα and β) and androgen receptor (AR) regulate various critical
processes during spermatogenesis. Since spermatogenesis is very sensitive to hormonal …

The identification of a second oestrogen receptor (beta) has prompted a re-evaluation of the
potential sites of action of oestrogens. The aim of the present study was to characterise …

Human and animal models have evidenced how estrogen insufficiency is associated with
abnormal spermatogenesis and male infertility. We previously demonstrated that estradiol is …

Estrogens, through their receptors, play an important role in regulation of spermatogenesis.
However, the precise role of the estrogen receptors (ESR1 and ESR2) has been difficult to …

Modulation of the testis-pituitary axis has direct relevance to the expression of androgen and
estrogen receptors. Androgen receptor (AR) and estrogen receptor (ERα) expression during …

Currently, clinical and experimental evidence point to an essential role of estrogens and
estrogen receptors in male fertility. The expression of estrogen receptor α (ERα) and β (ERβ) …

Maintenance of normal male fertility relies on the process of spermatogenesis which is
under complex endocrine control by mechanisms involving gonadotropin and steroid …

By the use of ribonuclease protection assay (RPA) combined with immunohistochemical
techniques, the expression of estrogen receptor (ER) α and ERβ was mapped in the …

Levels of estrogen within the male reproductive tract are higher than in the general
circulation and the aromatase enzyme is expressed in the adult testis. Estrogens such as …

BACKGROUND: The central role of estrogens and androgens in the male reproductive
system has focused attention on the presence and distribution of their cognate receptors …