Background The ability of bacteria to rapidly evolve resistance to antibiotics is a critical
public health problem. Resistance leads to increased disease severity and death rates, as …

Pseudomonas aeruginosa is an opportunistic pathogen that causes a wide range of acute
and chronic infections. An increasing number of isolates have mutations that make them …

Rapid progress in next generation sequencing and allied computational tools have aided in
identification of single nucleotide variants in genomes of several organisms. In the present …

Emerging resistance to antimicrobials and the lack of new antibiotic drug candidates
underscore the need for optimization of current diagnostics and therapies to diminish the …

Pseudomonas aeruginosa displays intrinsic resistance to many antibiotics and known to
acquire actively genetic mutations for further resistance. In this study, we attempted to …

The emergence of antimicrobial drug resistance is of enormous public concern due to the
increased risk of delayed treatment of infections, the increased length of hospital stays, the …

Many clinical isolates of Pseudomonas aeruginosa cause infections that are difficult to
eradicate due to their resistance to a wide variety of antibiotics. Key genetic determinants of …

Antimicrobial resistance (AMR) is now recognized as a global threat to human health. The
accessibility of microbial whole-genome sequencing offers an invaluable opportunity for …

Background Multidrug-resistant Pseudomonas aeruginosa has become a hazard to public
health, making medical treatment challenging and ineffective. Whole-genome sequencing …

One of the most striking features of Pseudomonas aeruginosa is its outstanding capacity for
developing antimicrobial resistance to nearly all available antipseudomonal agents through …