[HTML][HTML] The role of astrocytic aquaporin-4 in synaptic plasticity and learning and memory

JI Szu, DK Binder - Frontiers in integrative neuroscience, 2016 - frontiersin.org
Aquaporin-4 (AQP4) is the predominant water channel expressed by astrocytes in the
central nervous system (CNS). AQP4 is widely expressed throughout the brain, especially at …

Aquaporin-4 promotes memory consolidation in Morris water maze

Y Fan, M Liu, X Wu, F Wang, J Ding, J Chen… - Brain Structure and …, 2013 - Springer
Abstract Aquaporin-4 (AQP4), the most abundant aquaporin in the brain, is polarized at the
glial end-feet facing peri-synaptic areas. AQP4 has been hypothesized to modulate water …

The role of aquaporin-4 in synaptic plasticity, memory and disease

JA Hubbard, JI Szu, DK Binder - Brain research bulletin, 2018 - Elsevier
Since the discovery of aquaporins, it has become clear that the various mammalian
aquaporins play critical physiological roles in water and ion balance in multiple tissues …

Involvement of aquaporin 4 in astrocyte function and neuropsychiatric disorders

M Xiao, G Hu - CNS neuroscience & therapeutics, 2014 - Wiley Online Library
Summary Aquaporin 4 (AQP 4) is the main water channel in the central nervous system
(CNS) and specifically localized to astrocyte processes. Recent studies indicate that AQP 4 …

Aquaporin-4 water channels and synaptic plasticity in the hippocampus

HE Scharfman, DK Binder - Neurochemistry international, 2013 - Elsevier
Abstract Aquaporin-4 (AQP4) is the major water channel expressed in the central nervous
system (CNS) and is primarily expressed in glial cells. Many studies have shown that AQP4 …

The potential roles of aquaporin 4 in Alzheimer's disease

YL Lan, J Zhao, T Ma, S Li - Molecular neurobiology, 2016 - Springer
Abstract Aquaporin 4 (AQP4) is the major water channel expressed in the central nervous
system (CNS), and it is primarily expressed in astrocytes. It has been studied in various brain …

Aquaporin 4 in astrocytes is a target for therapy in Alzheimer's disease

YL Lan, JJ Chen, G Hu, J Xu, M Xiao… - Current Pharmaceutical …, 2017 - ingentaconnect.com
Current experimental evidence points to the conclusion that aquaporin 4 (AQP4), which is
an important water-channel membrane protein found in the brain, could play major roles in …

Chronic ceftriaxone treatment rescues hippocampal memory deficit in AQP4 knockout mice via activation of GLT-1

J Yang, MX Li, Y Luo, T Chen, J Liu, P Fang, B Jiang… - …, 2013 - Elsevier
Abstract Aquaporin-4 (AQP4) is the predominant water channel protein in the mammalian
brain, and is mainly expressed in astrocytes. Besides its important role in water transport …

Impairment of select forms of spatial memory and neurotrophin-dependent synaptic plasticity by deletion of glial aquaporin-4

VA Skucas, IB Mathews, J Yang, Q Cheng… - Journal of …, 2011 - Soc Neuroscience
Aquaporin-4 (AQP4) is the major water channel in the CNS and is primarily expressed in
astrocytes. Little is known about the potential for AQP4 to influence synaptic plasticity …

Regulation of water permeability through aquaporin-4

Y Yukutake, M Yasui - Neuroscience, 2010 - Elsevier
Aquaporin-4 (AQP4) is a predominant water channel protein in mammalian brains that is
distributed with the highest density in the perivascular and subpial astrocyte end-feet. AQP4 …