Purpose The purpose of the study was to demonstrate the performance and possible
applications of an intravital microscopy assay using a standard fluorescence microscope …

To grow and progress, solid tumors develop a vascular network through co-option and
angiogenesis that is characterized by multiple structural and functional abnormalities, which …

Angiogenesis and microcirculation play a central role in growth and metastasis of human
neoplasms, and, thus, represent a major target for novel treatment strategies. Mechanistic …

In current report we present synchronized in vivo imaging of tumor vascular network and
tumor microenvironment obtained by combined use of Dynamic Light Scattering Imaging …

We present a multi‐modal optical diagnostic approach utilizing a combined use of
Fluorescence Intravital Microscopy (FIM), Dynamic Light Scattering (DLS) and Spectrally …

To visualize the blood flow in the neovasculature of a solid tumor tissue, we utilized an
intravital microscope system equipped with real-time confocal laser scanning optics …

Tumour vessels have been studied extensively as they are critical sites for drug delivery, anti-
angiogenic therapies and immunotherapy. As a preclinical tool, intravital microscopy (IVM) …

The blood supply of solid tumours affects the outcome of treatment via its influence on the
microenvironment of tumour cells and drug delivery. In addition, tumour blood vessels are …

Real-time evaluation of vascular effects in an animal skinfold window model by intravital
microscopy (IVM) provides a powerful tool to improve insight into vascular development and …

Tumor and tumor vessel development, as well as tumor response to therapeutics, are highly
dynamic biological processes. Histology provides static information and is often not sufficient …