Aims Metabolic syndrome (MS) is a cluster of cardio-metabolic risk factors associated with
atherosclerosis and low-grade inflammation. Using unbiased expression screenings in …

Aims ATP-binding cassette transporter A1 (ABCA1) mediates the efflux of cholesterol and
phospholipids to lipid-poor apolipoproteins, which then form nascent HDL, a key step in the …

Objective—The ATP-binding cassette transporter A1 (ABCA1) is a major regulator of
macrophage cholesterol efflux and protects cells from excess intracellular cholesterol …

Objective Previous studies suggest that IL-8 has an important role in the regulation of
cholesterol efflux, but whether miRNAs are involved in this process is still unknown. The …

Objective—The ATP-binding cassette transporter A1 (ABCA1) protein maintains cellular
cholesterol homeostasis in several different tissues. In the liver, ABCA1 is crucial for high …

Hazen and Smith An Antiatherosclerotic Signaling Cascade 949 low-circulating systemic
levels. 16 The limited bioavailability of ingested anthocyanins has raised questions of a …

Purpose Cholesterol efflux from macrophages to HDL, measured in vitro, is augmented by
treatment with agents which raise HDL cholesterol. In vitro, cholesterol depletion by statins is …

Metabolic syndrome (MetS) is a complicated health problem that encompasses a variety of
metabolic disorders. In this study, we analyzed the relationship between the major …

ATP-binding cassette transporter A1 (ABCA1) plays a crucial role in reverse cholesterol
transport and exhibits anti-atherosclerosis effects. Some microRNAs (miRs) regulate ABCA1 …

Aim: ATP-binding cassette (ABC) transporters and endonuclease-exonuclease-
phosphatase family domain containing 1 (EEPD1) are reported to regulate cellular …