Characteristics of a cost-effective blood test for colorectal cancer screening

P Nascimento De Lima… - JNCI: Journal of the …, 2024 - academic.oup.com
Background Blood-based biomarker tests can potentially change the landscape of colorectal
cancer (CRC) screening. We characterize the conditions under which blood test screening …

Comparative effectiveness and cost-effectiveness of colorectal cancer screening with blood-based biomarkers (liquid biopsy) vs fecal tests or colonoscopy

U Ladabaum, A Mannalithara, Y Weng, RE Schoen… - Gastroenterology, 2024 - Elsevier
Background & Aims Colorectal cancer (CRC) screening is highly effective but underused.
Blood-based biomarkers (liquid biopsy) could improve screening participation. Methods …

[HTML][HTML] Effectiveness and cost-effectiveness of colorectal cancer screening with a blood test that meets the Centers for Medicare & Medicaid Services coverage …

R van den Puttelaar, PN de Lima, AB Knudsen… - Gastroenterology, 2024 - Elsevier
Background & Aims A blood-based colorectal cancer (CRC) screening test may increase
screening participation. However, blood tests may be less effective than current guideline …

Cost-Effectiveness of Blood-Based Biomarkers for Colorectal Cancer Screening—An Ounce of Prevention Is Worth a Pound of Cure

JM Inadomi - JAMA Network Open, 2023 - jamanetwork.com
There are several timely, important, and novel aspects to colorectal cancer (CRC) screening
that are highlighted in the study by Aziz et al. 1 Despite good evidence to illustrate the …

Differential impact of test performance characteristics on burden-to-benefit tradeoffs for blood-based colorectal cancer screening: A microsimulation analysis

A Piscitello, LN Carroll, S Fransen… - Journal of Medical …, 2023 - journals.sagepub.com
Objectives To inform the development and evaluation of new blood-based colorectal cancer
(CRC) screening tests satisfying minimum United States (US) coverage criteria, we …

Blood-based tests for colorectal cancer screening: do they threaten the survival of the FIT test?

RS Bresalier, S Kopetz, DE Brenner - Digestive diseases and sciences, 2015 - Springer
Colorectal cancer is the second leading cause of cancer death in industrialized nations,
accounting for 10% of the total cancer burden with an individual lifetime risk of~ 6% in the …

[HTML][HTML] Development of an algorithm combining blood-based biomarkers, fecal immunochemical test, and age for population-based colorectal cancer screening

MM Petersen, J Kleif, J Liggett, M Rasmussen… - Gastrointestinal …, 2024 - Elsevier
Background and Aims Implementation of screening modalities have reduced the burden of
colorectal cancer (CRC), but high false positive rates pose a major problem for colonoscopy …

Cost-effectiveness of high-performance biomarker tests vs fecal immunochemical test for noninvasive colorectal cancer screening

I Lansdorp-Vogelaar, SL Goede, LJW Bosch… - Clinical …, 2018 - Elsevier
Background & Aims Biomarker assays could increase the accuracy of noninvasive detection
of colorectal cancer (CRC); fecal immunochemical tests (FITs) are estimated to miss 27 …

[HTML][HTML] Optimizing screening for colorectal cancer: an algorithm combining fecal immunochemical test, blood-based cancer-associated proteins and demographics to …

MM Petersen, J Kleif, LN Jørgensen, JW Hendel… - Clinical colorectal …, 2023 - Elsevier
Abstract Background Fecal Immunochemical Test (FIT) is widely used in population-based
screening for colorectal cancer (CRC). This had led to major challenges regarding …

Counting advanced precancerous lesions as true positives when determining colorectal cancer screening test specificity

U Ladabaum, TR Church, Z Feng… - JNCI: Journal of the …, 2022 - academic.oup.com
Abstract The landmark Centers for Medicare & Medicaid Services (CMS) decision memo on
blood-based biomarkers to screen for colorectal cancer (CRC) sets thresholds of 74% or …