Acetylcholine (ACh), an ubiquitous mediator substance broadly expressed in nature, acts as
neurotransmitter in cholinergic synapses, generating specific communications with different …

Abstract Until 1950–1960, most physiologists were reluctant to accept chemical
neurotransmission. They believed that chemical reactions were much too slow to account for …

There are two quite distinct types of cholinergic transmission in the vertebrate nervous
system: a rapid form, mediated via nicotinic receptors; and a slow form, mediated via …

At cholinergic synapses, acetylcholinesterase (AChE) is critical for ensuring normal synaptic
transmission. However, little is known about how this enzyme is maintained and regulated in …

The concept of cholinergic neurotransmission sensu stricto, that cholinergic neurons
transmit information solely by releasing the small molecular mass endogenous …

The present study was performed to evaluate the presence and the physiological
consequences of butyrylcholinesterase (BChE) inhibition on isolated phrenic …

Traditional descriptions of the cortical cholinergic input system focused on the diffuse
organization of cholinergic projections and the hypothesis that slowly changing levels of …

The nicotinic acetylcholine (ACh) receptor is responsible for rapid conversion of chemical
signals to electrical signals at the neuromuscular junction. Because the receptor and its ion …

1. Acetylcholine (ACh) represents one of the most exemplary neurotransmitters. In addition
to its presence in neuronal tissue, there is increasing experimental evidence that ACh is …

Acetylcholinesterase (AChE) is an enzyme that terminates acetylcholine neurotransmitter
function at the synaptic cleft of cholinergic synapses. However, the mechanism by which …