Alzheimer's disease (AD) is an aging-dependent, irreversible neurodegenerative disorder
and the most common cause of dementia. The prevailing AD hypothesis points to the central …

An excess of saturated fatty acids and simple sugars in the diet is a known environmental
risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes …

The Alzheimer's disease (AD) brain shows numerous pathological phenomena, including
amyloid plaques, neurofibrillary tangles, elevated levels of advanced glycation endproducts …

Sustained brain chronic inflammation in Alzheimer's disease (AD) includes glial cell
activation, an increase in cytokines and chemokines, and lipid mediators (LMs), concomitant …

Food restriction has been widely associated with beneficial effects on brain aging and age-
related neurodegenerative diseases such as Alzheimer's disease. However, previous …

Alzheimer's disease (AD) is mainly characterized by the accumulation and aggregation of
amyloid-β (Aβ) peptides in brain parenchyma and cerebral microvasculature. Unfortunately …

Studies have assessed individual components of a western diet, but no study has assessed
the long-term, cumulative effects of a western diet on aging and Alzheimer's disease (AD) …

Background Alzheimer's disease (AD) is the most common neurodegenerative disease
causing dementia in the elderly population. Due to the fact that there is still no cure for …

Diet is a modifiable risk factor for Alzheimer's disease (AD), but the mechanisms linking
alterations in peripheral metabolism and cognition remain unclear. Since it is especially …

Background: Ample evidence from clinical and pre-clinical studies suggests mid-life
hypercholesterolemia as a risk factor for developing Alzheimer's disease (AD) at a later age …