Chronic inflammation is known to play a critical role in cancer development and progression.
High salt is known to mediate several chronic inflammatory diseases including hypertension …

Chronic inflammation has been considered an important player in cancer proliferation and
progression. High salt (sodium chloride) levels have been considered a potent inducer of …

Excess salt intake could affect the immune system by shifting the immune cell balance
toward a pro-inflammatory state. Since this shift of the immune balance is thought to be …

Objective Dietary patterns are believed to regulate tumor progression by altering the tumor
microenvironment. Of note, a high salt diet is a risk factor for various diseases. However, the …

Chronic inflammation is a well-known precursor for cancer development and proliferation.
We have recently demonstrated that high salt (NaCl) synergizes with sub-effective …

High-salt diets are associated with an elevated risk of autoimmune diseases, and immune
dysregulation plays a key role in cancer development. However, the correlation between …

Recent evidence from our laboratory has demonstrated that high salt (Δ0. 05 M NaCl)
induced inflammatory response and cancer cell proliferation through salt inducible kinase-3 …

The microenvironment of solid tumors is often acidic due to poor vascular perfusion, regional
hypoxia, and increased glycolytic activity of tumor cells. Although acidosis is harmful to most …

Salt sensitivity concerns blood pressure alterations after a change in salt intake (sodium
chloride). The heart is a pump, and vessels are tubes; sodium can affect both. A high salt …

A precise maintenance of sodium and fluid balance is an essential step in the regulation of
blood pressure and alterations of this balance may lead to the development of hypertension …