The effect of lung deformation on the spatial distribution of pulmonary blood flow

TJ Arai, RJ Theilmann, RC Sá… - The Journal of …, 2016 - Wiley Online Library
Key points Pulmonary perfusion measurement using magnetic resonance imaging
combined with deformable image registration enabled us to quantify the change in the …

Effects of respiratory cycle and body position on quantitative pulmonary perfusion by MRI

JJ Cao, YI Wang, W Schapiro… - Journal of Magnetic …, 2011 - Wiley Online Library
Purpose: To evaluate the performance of lung perfusion imaging using two‐dimensional
(2D) first pass perfusion MRI and a quantitation program based on model‐independent …

Lung perfusion measured using magnetic resonance imaging: new tools for physiological insights into the pulmonary circulation

SR Hopkins, GK Prisk - Journal of Magnetic Resonance …, 2010 - Wiley Online Library
Since the lung receives the entire cardiac output, sophisticated imaging techniques are not
required in order to measure total organ perfusion. However, for many years studying lung …

The effect of supine exercise on the distribution of regional pulmonary blood flow measured using proton MRI

ET Hall, RC Sá, S Holverda, TJ Arai… - Journal of Applied …, 2014 - journals.physiology.org
The Zone model of pulmonary perfusion predicts that exercise reduces perfusion
heterogeneity because increased vascular pressure redistributes flow to gravitationally …

The spatial-temporal dynamics of pulmonary blood flow are altered in pulmonary arterial hypertension

AS Kizhakke Puliyakote, GK Prisk… - Journal of Applied …, 2023 - journals.physiology.org
Global fluctuation dispersion (FDglobal), a spatial-temporal metric derived from serial
images of the pulmonary perfusion obtained with MRI-arterial spin labeling, describes …

Effects of age on pulmonary perfusion heterogeneity measured by magnetic resonance imaging

DL Levin, RB Buxton, JP Spiess… - Journal of applied …, 2007 - journals.physiology.org
Normal aging is associated with a decline in pulmonary function and efficiency of gas
exchange, although the effects on the spatial distribution of pulmonary perfusion are poorly …

Assessment of differential pulmonary blood flow using perfusion magnetic resonance imaging: comparison with radionuclide perfusion scintigraphy

F Molinari, C Fink, F Risse, S Tuengerthal… - Investigative …, 2006 - journals.lww.com
Objectives: We sought to assess the agreement between lung perfusion ratios calculated
from pulmonary perfusion magnetic resonance imaging (MRI) and those calculated from …

Pulmonary blood flow redistribution by increased gravitational force

MP Hlastala, MA Chornuk, DA Self… - Journal of Applied …, 1998 - journals.physiology.org
This study was undertaken to assess the influence of gravity on the distribution of pulmonary
blood flow (PBF) using increased inertial force as a perturbation. PBF was studied in …

Vertical gradients in regional lung density and perfusion in the supine human lung: the Slinky effect

SR Hopkins, AC Henderson, DL Levin… - Journal of applied …, 2007 - journals.physiology.org
In vivo radioactive tracer and microsphere studies have differing conclusions as to the
magnitude of the gravitational effect on the distribution of pulmonary blood flow. We …

Lung volume does not alter the distribution of pulmonary perfusion in dependent lung in supine humans

SR Hopkins, TJ Arai, AC Henderson… - The Journal of …, 2010 - Wiley Online Library
There is a gravitational influence on pulmonary perfusion, including in the most dependent
lung, where perfusion is reduced, termed Zone 4. Studies using xenon‐133 show Zone 4 …