Functional lung imaging has the potential to offer many new insights into mechanisms of
pulmonary disease. While the physiologist has access to a number of techniques to evaluate …

This study aims to assess regional ventilation, nonlinearity, and hysteresis of human lungs
during dynamic breathing via image registration of four-dimensional computed tomography …

How the heterogeneous distribution of lung volumes changes in response to different
mechanical ventilation (MV) strategies is unclear. Using our well-developed four …

Background Due to the different properties of the contrast agents, the lung perfusion maps
as measured by 99mTc-labeled macroaggregated albumin perfusion scintigraphy (PS) are …

Recent experimental and imaging studies suggest that the influence of gravity on the
measured distribution of blood flow in the lung is largely through deformation of the …

Background—Cardiac hemodynamics affect pulmonary vascular pressure and flow, but little
is known of the effects of hemodynamics on lung perfusion at the tissue level. We sought to …

Purpose To investigate dynamic contrast‐enhanced MRI (DCE‐MRI) for quantification of
pulmonary blood flow (PBF) and blood volume (PBV) using the prebolus approach and to …

To examine the effect of cardiac output (CO) on the gravity-nondependent distribution of
pulmonary blood flow, 2 X 10 (6) 99mTc-labeled albumin microspheres (20 microns) were …

Purpose To assess regional differences in quantitative pulmonary perfusion parameters, ie,
pulmonary blood flow (PBF), mean transit time (MTT), and pulmonary blood volume (PBV) in …