The larval midgut in holometabolous insects must undergo a remodeling process during
metamorphosis to form the pupal-adult midgut. However, the molecular mechanism of larval …

The life cycle of holometabolous insects involves different stages and cathepsin plays an
important role in insect metamorphosis. In the present study, we investigated the function of …

Holometabolous insects undergo larval moulting and metamorphosis within their life cycle. A
cDNA encoding the cathepsin L‐like proteinase Ha‐cathL has been cloned from …

Cathepsin L-like proteinases (CAL) are major digestive proteinases in the beetle Tenebrio
molitor. Procathepsin Ls 2 (pCAL2) and 3 (pCAL3) were expressed as recombinant proteins …

Midgut tissue undergoes remodeling during metamorphosis in insects belonging to orders
Lepidoptera and Diptera. We investigated the developmental and hormonal regulation of …

Proteolytic enzymes are involved in insect molting and metamorphosis, and play a vital role
in the programmed cell death of obsolete organs. Here we show the expression profile of …

Programmed cell death (PCD) is crucial in body restructuring during metamorphosis of
holometabolous insects (those that have a pupal stage between the final larval and adult …

We previously described the most highly expressed enzymes from the gut of the red flour
beetle, Tribolium castaneum, as cathepsins L. In the present study, two C1 family-specific …

CDNAs coding for five procathepsin L-like proteinases (pCALs) were cloned and sequenced
from a cDNA library prepared from Tenebrio molitor larval midguts: pCAL1a (with the …

Midgut remodeling is a complex physiological process in holometabolous insects. During
midgut remodeling, the larval midgut is decomposed by apoptosis or autophagy during …