[图书][B] Investigating the Roles of Francisella Encoded Factors and NLRP3 in Immunopathogenesis of Tularemia

RV Suresh - 2018 - search.proquest.com
Francisella tularensis (F. tularensis) is a Gram-negative bacterium that causes the fatal
disease known as tularemia. It is an intracellular pathogen that can infect a wide variety of …

Nlrp3 increases the host's susceptibility to tularemia

RV Suresh, EW Bradley, M Higgs, VC Russo… - Frontiers in …, 2021 - frontiersin.org
Francisella tularensis (F. tularensis) is a Gram-negative, intracellular bacterium and the
causative agent of a fatal human disease known as tularemia. The CDC has classified F …

Repression of inflammasome by Francisella tularensis during early stages of infection

RJ Dotson, SM Rabadi, EL Westcott, S Bradley… - Journal of Biological …, 2013 - ASBMB
Francisella tularensis is an important human pathogen responsible for causing tularemia. F.
tularensis has long been developed as a biological weapon and is now classified as a …

Characterization of the Role of Francisella‐Sensing Inflammasomes in the Development of Innate and Vaccine‐Induced Immunity

M Alqahtani - 2020 - touroscholar.touro.edu
Francisella tularensis is a highly virulent, facultative intracellular, Gram‐negative bacterium
that causes fatal zoonotic disease tularemia. The inflammasome is a multiprotein complex …

[图书][B] The Role of NLRP3 in Modulating Innate Immune Responses Against Francisella tularensis

EL Westcott - 2016 - search.proquest.com
Francisella tularensis is a gram-negative intracellular pathogen and the causative agent of a
fatal zoonotic disease known as tularemia. Due to its high virulence, ease of aerosolization …

[PDF][PDF] The role of AIM2 and NLRP12 in the innate immune response to Francisella tularensis

TK Ulland - 2014 - iro.uiowa.edu
The innate immune response to pathogens by the host is dependent upon the interplay of
both pathogen and host intrinsic factors. Nucleotide-‐binding domain leucine-‐rich repeat …

MviN mediates Francisella tularensis virulence through evasion of AIM2 inflammasome activation

TK Ulland - 2010 - search.proquest.com
The mechanisms by which the facultative intracellular pathogen Francisella tularensis is
recognized by the innate immune system and the strategies that F. tularensis uses to avoid …

Innate Immune Recognition of Francisella Tularensis: Activation of Type-I Interferons and the Inflammasome

JW Jones, P Broz, DM Monack - Frontiers in microbiology, 2011 - frontiersin.org
Francisella tularensis is an intracellular pathogen that can cause severe disease in a wide
range of mammalian hosts. Primarily residing in host macrophages, F. tularensis escapes …

NLRP3 directs inflammasome activation in response to live F. tularensis infection (42.20)

M Atianand, A Shah, E Duffy, S Kar… - The Journal of …, 2010 - journals.aai.org
Detection of intracellular pathogens is facilitated by members of the nucleotide binding-
leucine rich receptor (NLR) family. The role of ASC/Caspase-1 axis for protective innate …

Aim2 and Nlrp3 are dispensable for vaccine-induced immunity against Francisella tularensis live vaccine strain

M Alqahtani, Z Ma, K Fantone, M Malik… - Infection and …, 2021 - Am Soc Microbiol
Francisella tularensis is a facultative, intracellular, Gram-negative bacterium that causes a
fatal disease known as tularemia. Due to its extremely high virulence, ease of spread by …