[HTML][HTML] Chemoprevention of prostate cancer in men with high-grade prostatic intraepithelial neoplasia (HGPIN): a systematic review and adjusted indirect treatment …

K Cui, X Li, Y Du, X Tang, S Arai, Y Geng, Y Xi, H Xu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Background High-grade prostatic intraepithelial neoplasia (HGPIN) is the precursor or
premalignant form of prostate cancer. At least 30% patients with a confirmed HGPIN will …

Green tea catechins for chemoprevention of prostate cancer in patients with histologically-proven HG-PIN or ASAP. Concise review and meta-analysis

G Perletti, V Magri, A Vral… - Archivio Italiano di …, 2019 - pagepressjournals.org
In conclusion, our data suggest that the intake of concentrated green tea catechin
preparations may confer a significant protective effect to carriers of early neoplastic lesions …

[HTML][HTML] Drug therapies for eradicating high-grade prostatic intraepithelial neoplasia in the prevention of prostate cancer

SS Taneja - Reviews in urology, 2005 - ncbi.nlm.nih.gov
High-grade prostatic intraepithelial neoplasia (HGPIN) is a precursor to invasive prostate
cancer observed as an isolated entity in a growing subset of men undergoing prostate …

Prostate cancer chemoprevention: strategies for designing efficient clinical trials

R Lieberman - Urology, 2001 - Elsevier
A chemoprevention (CP) strategy has evolved for conducting efficient clinical trials for
prostate cancer (PCa) prevention. It integrates five key components, including agents …

Randomized, placebo-controlled trial of green tea catechins for prostate cancer prevention

NB Kumar, J Pow-Sang, KM Egan, PE Spiess… - Cancer Prevention …, 2015 - AACR
Preclinical, epidemiologic, and prior clinical trial data suggest that green tea catechins
(GTC) may reduce prostate cancer risk. We conducted a placebo-controlled, randomized …

Prostate cancer diagnosis among men with isolated high-grade intraepithelial neoplasia enrolled onto a 3-year prospective phase III clinical trial of oral toremifene

SS Taneja, R Morton, G Barnette, P Sieber… - Journal of clinical …, 2013 - ascopubs.org
Purpose Prostate cancer (PCa) prevention remains an appealing strategy for the reduction
of overtreatment and secondary adverse effects. We evaluated the efficacy of toremifene …

Effect of green tea catechins in patients with high-grade prostatic intraepithelial neoplasia: Results of a short-term double-blind placebo controlled phase II clinical trial

S Micali, A Territo, GM Pirola, N Ferrari… - ARCHIVIO ITALIANO …, 2017 - iris.unimore.it
Background and study objective: Several studies suggest a protective role of green tea
catechins against prostate cancer (PCa). In order to evaluate the efficacy of green tea …

[HTML][HTML] Green tea extract for prevention of prostate cancer progression in patients on active surveillance

NB Kumar, SI Dickinson, MJ Schell, BJ Manley… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Background Active surveillance (AS) has evolved as a management strategy for men with
low grade prostate cancer (PCa). However, these patients report anxiety, doubts about the …

A randomized double‐blind placebo controlled phase I–II study on clinical and molecular effects of dietary supplements in men with precancerous prostatic lesions …

P Gontero, G Marra, F Soria, M Oderda, A Zitella… - The …, 2015 - Wiley Online Library
BACKGROUND Antioxidants effectiveness in prostate cancer (PCa) chemoprevention has
been severely questioned, especially after the recent results of the Selenium and Vitamin E …

Cancer progress and priorities: prostate cancer

KH Kensler, TR Rebbeck - Cancer Epidemiology, Biomarkers & Prevention, 2020 - AACR
Background Prostate cancer is the second most common cancer globally among men,
although incidence and mortality rates vary greatly between countries and there are large …