Aim In this study, we aimed to evaluate the association between genetic variants of ZC3HC1
and SMARCA4 and hypertension risk in the Chinese Han population. Methods The Agena …

BACKGROUND The large-scale meta-analysis of genome-wide association study (GWAS)
recently identified a genomic locus where the genetic variant at rs820430 was strongly …

Converging evidence suggests that the gene encoding solute carrier family 12 member 3
(SLC12A3) is a logical candidate involved in the underlying cause of hypertension. We …

The dopamine transporter SLC6A3 (DAT1) mediates uptake of dopamine into presynaptic
terminals. In addition, in previous reports, hypertensive rats were associated with DAT gene …

Background The rs41318021 polymorphism in the SLC7A1 gene affects endothelial NO
production through changes in L-arginine transport. This variation could thus hypothetically …

Objective: SLC12A3 (solute carrier family 12 member 3) gene variants are associated with
diabetic nephropathy; however, their association with hypertensive nephropathy remains …

Aims Diabetes mellitus and hypertension are both complex diseases that are caused by
interactions among multiple genetic and physiological factors. To investigate the association …

Background Hypertension is a major risk factor for cardiovascular disease. Although genetic
studies have suggested that several genetic variants increase the risk for hypertension, the …

Objective: Genetic factors are involved in the occurrence, development, and progression of
essential hypertension (EH). To study the association between single nucleotide …

BACKGROUND Although the genetic factors associated with hypertension remain unknown,
genetic variations in genes related to ion channels, inflammation, and the cell cycle may …