Hypertension is a complex disorder with high prevalence rates all over the world. We
conducted the first genome-wide gene-based association scan for hypertension in a Han …

Background: A recent genome-wide linkage study mapped blood pressure (BP)-related loci
on human chromosome 1q and identified the regulator of G-protein signaling 5 (RGS5) as a …

INSR and ISR‑1 may be candidate genes for essential hypertension (EH). However, the
genetic association between the INSR and ISR‑1 gene polymorphisms and EH risk remains …

Findings of previous studies demonstrated that rs6007897 (C→ T, Ala2268Thr) of the
cadherin, epidermal growth factor (EGF) laminin AG‑type repeats (LAG) seven‑pass G‑type …

Background Compared with patients who require fewer antihypertensive agents, those with
apparent treatment-resistant hypertension (aTRH) are at increased risk for cardiovascular …

Hypertension is a common disorder and the leading risk factor for cardiovascular disease
and premature deaths worldwide. Genome-wide association studies (GWASs) in the …

OBJECTIVE: A recent genome wide association study identified eight hypertension
susceptibility loci in Europeans. Subsequently, several studies have investigated these …

Background Hypertension is rising as a major public health burden around the world. This
study explored the association between single-nucleotide polymorphisms (SNPs) in the …

In a recent genome-wide association study, the zinc finger, C3HC-type containing 1
(ZC3HC1) polymorphism was strongly associated with coronary artery disease (CAD) by an …

Essential hypertension (EH) is thought to result from the interaction of environmental and
genetic factors. The molecular genetics of EH has witnessed considerable progress during …