BACKGROUND Childhood hypertension is a complex disease influenced by both genetic
and environmental factors. We aimed to examine how obesity status influences the …

To estimate the associations between single-nucleotide polymorphisms (SNPs) and
methylation of SLC30A8 gene and T2DM risk, and the interactions among SNPs …

Essential hypertension is considered to be a typical complex disease with multifactorial
etiology, which leads to inconsistent findings in genetic studies. One possibility of failure to …

Recent genome-wide association studies have identified several single-nucleotide
polymorphisms (SNPs) that are associated with blood pressure (BP)/hypertension. In this …

Introduction High blood pressure is widely regarded as the most important risk factor for
cardiovascular diseases. Epistasis analysis may provide additional insight into the genetic …

Many genetic association studies support a contribution of genetic variants in the KCNJ11-
ABCC8 gene locus to type 2 diabetes (T2D) susceptibility in Caucasians. In non-Caucasian …

Objective Although an increasing number of hypertension-associated genetic variants is
being reported, replication of these findings in independent studies has been challenging …

Objective In the past few decades, consumption of added sugars has increased
dramatically. Studies have linked high sugar intake with increased risk for a number of …

Med., 2006, 208 (1), 25-31── We investigated the possible association of solute carrier
family 6 member 18 (SLC6A18) with hypertension and blood pressure in Japanese, since …

Background Type 2 diabetes mellitus (T2DM) is a chronic and multifactorial disease with a
rapidly rising incidence in Saudi Arabia. Various genes including zinc finger protein 1 …