Various loci and genes that confer susceptibility to coronary artery disease (CAD) have been
identified mainly in Caucasian populations by genome‑wide association studies (GWASs) …

Many studies have suggested that transforming growth factor-β1 (TGF-β1) gene might be
involved in the development of hypertension. However, results have been inconsistent. In …

Objective To verify the linkage of the candidate regions identified in a previous study
(markers D2S168, D2S151, D2S142 on chromosome 2) with hypertension in Chinese …

Objective To assess the association between single nucleotide polymorphisms (SNPs) of
calcium channel β 2 subunit (CACNB2) gene and essential hypertension (EH) in ethnic Han …

Background: Essential hypertension arises from the combined effect of genetic and
environmental factors. A pharmacogenomics approach could help to identify additional …

BACKGROUND Hypertension (HTN) and type 2 diabetes mellitus (T2DM) are often
coincident, and each condition is considered a risk factor for the other. Both occur frequently …

The mechanisms orchestrating the balance between nitric oxide and endothelium-derived
contracting factors, and genetic predisposition to endothelial dysfunction in hypertensive …

Background and Objective Via direct sequencing, we have recently identified six common
polymorphisms in angiotensin receptor-like 1 (AGTRL1) gene, and found only two …

Background Type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) are two
deadly diseases caused by the complex interaction of multiple genetic loci, lifestyle and …

Hypertension tends to perpetuate in families and the heritability of hypertension is estimated
to be around 20–60%. So far, the main proportion of this heritability has not been found by …