With more than 80 subunits, potassium (K+) channels represent a group of ion channels
showing high degree of diversity and ubiquity. They play important role in the control of …

ATP-sensitive potassium channels (K ATP channels), a group of vital channels that link the
electrical activity of the cell membrane with cell metabolism, were discovered on the …

Population aging, as well as the handling of age-associated diseases, is a worldwide
increasing concern. Among them, Alzheimer's disease stands out as the major cause of …

Potassium (K+) channels are encoded by approximately 80 genes in mammals. They are
expressed in many tissues and have diverse physiological roles. Human K+ channels are …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by selective loss of
dopaminergic neurons in the substantia nigra pars compacta (SNpc) region of the midbrain …

Voltage-gated potassium (Kv) channels are widely expressed in the central and peripheral
nervous system and are crucial mediators of neuronal excitability. Importantly, these …

The growing interest in the role of microglia in the progression of many neurodegenerative
diseases is developing in an ever-expedited manner, in part thanks to emergent new tools …

Within the potassium ion channel family, calcium activated potassium (KCa) channels are
unique in their ability to couple intracellular Ca2+ signals to membrane potential variations …

Introduction 3. Potassium channel diversity and classifications 3.1. Classifications and
structure of potassium channels 3.1. 1. Voltage-gated K+ channels 3.1. 2. Calcium-activated …

Parkinson's disease (PD) is the second most common neurodegenerative disorder, which is
associated with a selective loss of dopaminergic neurons in the substantia nigra (SN) and a …