[PDF][PDF] Chemogenetic dissection of prefrontal signalling underlying attention and impulsivity
B van der Veen - 2022 - oparu.uni-ulm.de
Attention and impulse control deficits are found in a wide variety of mental disorders from
attention deficit/hyperactivity disorder (ADHD), major depression, schizophrenia to …
attention deficit/hyperactivity disorder (ADHD), major depression, schizophrenia to …
Control of impulsivity by Gi-protein signalling in layer-5 pyramidal neurons of the anterior cingulate cortex
B Van der Veen, SKT Kapanaiah, K Kilonzo… - Communications …, 2021 - nature.com
Pathological impulsivity is a debilitating symptom of multiple psychiatric diseases with few
effective treatment options. To identify druggable receptors with anti-impulsive action we …
effective treatment options. To identify druggable receptors with anti-impulsive action we …
Neural and psychological mediators of trait impulsivity: cortico-striatal circuitry and catecholaminergic neuromodulation
C Toschi - 2022 - repository.cam.ac.uk
Impulsivity is a multidimensional trait in humans and other mammalian species. It is widely
regarded as the tendency to act rapidly, without appropriate foresight and underlies many …
regarded as the tendency to act rapidly, without appropriate foresight and underlies many …
Dissociable effects of mGluR5 allosteric modulation on distinct forms of impulsivity in rats: interaction with NMDA receptor antagonism
SN Isherwood, A Pekcec, JR Nicholson… - …, 2015 - Springer
Rationale Impaired N-methyl-d-aspartate (NMDA) receptor signalling underlies several
psychiatric disorders that express high levels of impulsivity. Although synergistic interactions …
psychiatric disorders that express high levels of impulsivity. Although synergistic interactions …
Double dissociation between serotonergic and dopaminergic modulation of medial prefrontal and orbitofrontal cortex during a test of impulsive choice
CA Winstanley, DEH Theobald, JW Dalley… - Cerebral …, 2006 - academic.oup.com
Dysregulation of the prefrontal cortex (PFC) has been implicated in impulse control
disorders, including attention deficit hyperactivity disorder. A growing body of evidence …
disorders, including attention deficit hyperactivity disorder. A growing body of evidence …
Differential gene expression in the mesocorticolimbic system of innately high-and low-impulsive rats
GM Moloney, WEPA van Oeffelen, FJ Ryan… - Behavioural Brain …, 2019 - Elsevier
Impulsivity is an important component of many psychiatric illnesses and has been
associated with a number of psychiatric disorders such as bipolar disorder and attention …
associated with a number of psychiatric disorders such as bipolar disorder and attention …
Neurobehavioral mechanisms of impulsivity: fronto-striatal systems and functional neurochemistry
Impulsive acts and decisions are a part of everyday normal behavior. However, in its
pathological forms, impulsivity can be a debilitating disorder often associated with a number …
pathological forms, impulsivity can be a debilitating disorder often associated with a number …
Inherent motor impulsivity associates with specific gene targets in the rat medial prefrontal cortex
DJ Sholler, CR Merritt, BD Davis-Reyes, G Golovko… - Neuroscience, 2020 - Elsevier
High impulsivity characterizes a myriad of neuropsychiatric diseases, and identifying targets
for neuropharmacological intervention to reduce impulsivity could reveal transdiagnostic …
for neuropharmacological intervention to reduce impulsivity could reveal transdiagnostic …
Methylphenidate and atomoxetine-responsive prefrontal cortical genetic overlaps in “impulsive” SHR/NCrl and Wistar rats
Impulsivity, the predisposition to act prematurely without foresight, is associated with a
number of neuropsychiatric disorders, including attention-deficit/hyperactivity disorder …
number of neuropsychiatric disorders, including attention-deficit/hyperactivity disorder …
Selective chemogenetic inactivation of corticoaccumbal projections disrupts trait choice impulsivity
Impulsive choice has enduring trait-like characteristics and is defined by preference for small
immediate rewards over larger delayed ones. Importantly, it is a determining factor in the …
immediate rewards over larger delayed ones. Importantly, it is a determining factor in the …