[HTML][HTML] Identification of potential biomarkers for psoriasis by DNA methylation and gene expression datasets

Y Liu, S Cui, J Sun, X Yan, D Han - Frontiers in Genetics, 2021 - frontiersin.org
DNA methylation (DNAm) plays an important role in the pathogenesis of psoriasis through
regulating mRNA expressions. This study aimed to identify hub genes regulated by DNAm …

Exploration of biomarkers of psoriasis through combined multiomics analysis

L Xing, T Wu, L Yu, N Zhou, Z Zhang… - Mediators of …, 2022 - Wiley Online Library
Background. Aberrant DNA methylation patterns are of increasing interest in the study of
psoriasis mechanisms. This study aims to screen potential diagnostic indicators affected by …

Integrative methylome and transcriptome analysis to dissect key biological pathways for psoriasis in Chinese Han population

L Tang, Y Cheng, C Zhu, C Yang, L Liu, Y Zhang… - Journal of …, 2018 - Elsevier
Background Recent studies have revealed that DNA methylation (DNAm) could modulate
gene expression in psoriasis (Ps). However, the relationship between whole-genome DNAm …

[HTML][HTML] Epigenome-wide DNA methylation regulates cardinal pathological features of psoriasis

A Chandra, S Senapati, S Roy, G Chatterjee… - Clinical …, 2018 - Springer
Background Psoriasis is a chronic inflammatory autoimmune skin disorder. Several studies
suggested psoriasis to be a complex multifactorial disease, but the exact triggering factor is …

[HTML][HTML] Epigenome-wide association analysis identified nine skin DNA methylation loci for psoriasis

F Zhou, W Wang, C Shen, H Li, X Zuo, X Zheng… - Journal of Investigative …, 2016 - Elsevier
Psoriasis is a chronic hyperproliferative and inflammatory skin disease caused by the
interplay of genetic and environmental factors. DNA methylation has been linked to …

[HTML][HTML] Network analysis of potential risk genes for psoriasis

H Wang, W Chen, J He, W Xu, J Liu - Hereditas, 2021 - Springer
Background Psoriasis is a complex chronic inflammatory skin disease. The aim of this study
was to analyze potential risk genes and molecular mechanisms associated with psoriasis …

[HTML][HTML] Epigenome-wide association data implicates DNA methylation-mediated genetic risk in psoriasis

F Zhou, C Shen, J Xu, J Gao, X Zheng, R Ko, J Dou… - Clinical …, 2016 - Springer
Background Psoriasis is a chronic inflammatory skin disease characterized by epidermal
hyperproliferation and altered keratinocyte differentiation and inflammation and is caused by …

[HTML][HTML] Genome-wide DNA methylation of Munro's microabscess reveals the epigenetic regulation in the pathogenesis of psoriasis

X Xu, Y Zhang, Z Pan, X Zhang, X Liu, L Tang… - Frontiers in …, 2022 - frontiersin.org
Introduction Munro's microabscess is a typical pathological feature in the early psoriatic
lesion, mainly characterized by the accumulation of neutrophils in the epidermis. DNA …

Whole-genome DNA methylation in skin lesions from patients with psoriasis vulgaris

P Zhang, M Zhao, G Liang, G Yin, D Huang, F Su… - Journal of …, 2013 - Elsevier
Psoriasis, a chronic inflammatory skin disorder, is characterized by aberrant keratinocyte
proliferation and differentiation in the epidermis. Although the pathogenesis of psoriasis is …

Epigenetics in psoriasis: perspective of DNA methylation

Y Luo, K Qu, L Kuai, Y Ru, K Huang, X Yan… - Molecular Genetics and …, 2021 - Springer
Psoriasis is a chronic inflammatory skin disease characterized by excessive proliferation of
keratinocytes (KCs). Onset of psoriasis is related to genetic, immune and environmental …