Downregulation of gap junctional intercellular communication and connexin 43 expression by bisphenol A in human granulosa cells

TC Lin, KH Wang, KH Chuang… - Biotechnology and …, 2021 - Wiley Online Library
Gap junctional intercellular communication (GJIC) is the transfer of ions, metabolites, and
second messengers between neighboring cells through intercellular junctions. Connexin 43 …

Inhibitory effect of bisphenol A on gap junctional intercellular communication in an epithelial cell line of rat mammary tissue

IK Lee, SK Rhee - Archives of pharmacal research, 2007 - Springer
An endocrine disruptor, bisphenol-A (BPA), has been reported to have several short-term
actions in various cells and tissues. However, the mechanisms of these actions have not …

Effects of bisphenol A on gap junctions in HaCaT cells as mediated by the estrogen receptor pathway

Q Zhang, S Wu, L Liu, X Hou, J Jiang… - Journal of Applied …, 2019 - Wiley Online Library
Bisphenol A (BPA) is widely used as the raw material for the production of plastics and
paper products. People can be exposed to BPA through dermal contact, particularly for …

The effects of 2-aminoethoxydiphenyl borate and diphenylboronic anhydride on gap junctions composed of connexin43 in TM4 sertoli cells

Y Yang, M Cao, Q Wang, D Yuan, L Li… - Biological and …, 2011 - jstage.jst.go.jp
2-Aminoethoxydiphenyl borate (2-APB) has recently been demonstrated to inhibit gap
junction (GJ) channels, whereas the underlying mechanisms are still unknown. Using …

BPA and BPS affect Connexin 37 in bovine cumulus cells

R Sabry, C Apps, JA Reiter-Saunders, AC Saleh… - Genes, 2021 - mdpi.com
Bisphenol S (BPS) is used as an alternative plasticizer to Bisphenol A (BPA), despite limited
knowledge of potential adverse effects. BPA exhibits endocrine disrupting effects during …

Betacellulin regulates gap junction intercellular communication by inducing the phosphorylation of connexin 43 in human granulosa-lutein cells

Y Li, HM Chang, YW Sung, H Zhu, PCK Leung… - Journal of Ovarian …, 2023 - Springer
Background The gap junction protein, connexin 43 (Cx43) is highly expressed in human
granulosa-lutein (hGL) cells. The phosphorylation of certain amino acid residues in the Cx43 …

[HTML][HTML] Modulation of Cx43 and gap junctional intercellular communication by androstenedione in rat polycystic ovary and granulosa cells in vitro

R Talhouk, C Tarraf, L Kobrossy, A Shaito… - … of reproduction & …, 2012 - ncbi.nlm.nih.gov
Background Gap-junctional intercellular communication (GJIC) is implicated in
physicological processes and it is vitally important for granulosa cell (GC) differentiation and …

[PDF][PDF] Lindane, a gap junction blocker, suppresses FSH and transforming growth factor beta1-induced connexin43 gap junction formation and steroidogenesis in rat …

FC Ke, SH Fang, MT Lee, SY Sheu, SY Lai… - J …, 2005 - joe.bioscientifica.com
The present study was designed to explore the role of gap junctions in follicle-stimulating
hormone (FSH) and transforming growth factor β1 (TGFβ1)-stimulated steroidogenesis in …

Bisphenol S enhances gap junction intercellular communication in ovarian theca cells

J Gingrich, Y Pu, BL Upham, M Hulse, S Pearl, D Martin… - Chemosphere, 2021 - Elsevier
Gap junction intercellular communication (GJIC) is necessary for ovarian function, and it is
temporospatially regulated during follicular development and ovulation. At outermost layer of …

Oocyte-derived BMP15 but not GDF9 down-regulates connexin43 expression and decreases gap junction intercellular communication activity in immortalized human …

HM Chang, JC Cheng, E Taylor… - Molecular human …, 2014 - academic.oup.com
In the ovary, connexin-coupled gap junctions in granulosa cells play crucial roles in follicular
and oocyte development as well as in corpus luteum formation. Our previous work has …