[HTML][HTML] Polygenic risk score for genetic evaluation of prostate cancer risk in Asian populations: A narrative review
SH Song, SS Byun - Investigative and clinical urology, 2021 - ncbi.nlm.nih.gov
Decreasing costs of genetic testing and interest in disease inheritance has changed the
landscape of cancer prediction in prostate cancer (PCa), and guidelines now include …
landscape of cancer prediction in prostate cancer (PCa), and guidelines now include …
Application of European‐specific polygenic risk scores for predicting prostate cancer risk in different ancestry populations
Background Polygenic risk score (PRS) has shown promise in predicting prostate cancer
(PCa) risk. However, the application of PRS in non‐European ancestry was poorly studied …
(PCa) risk. However, the application of PRS in non‐European ancestry was poorly studied …
Clinical validity and utility of genetic risk scores in prostate cancer
Current issues related to prostate cancer (PCa) clinical care (eg, over-screening, over-
diagnosis, and over-treatment of nonaggressive PCa) call for risk assessment tools that can …
diagnosis, and over-treatment of nonaggressive PCa) call for risk assessment tools that can …
[HTML][HTML] How Well do Polygenic Risk Scores Identify Men at High Risk for Prostate Cancer? Systematic Review and Meta-Analysis
A Siltari, R Lönnerbro, K Pang, K Shiranov… - Clinical genitourinary …, 2023 - Elsevier
Objectives Genome-wide association studies have revealed over 200 genetic susceptibility
loci for prostate cancer (PCa). By combining them, polygenic risk scores (PRS) can be …
loci for prostate cancer (PCa). By combining them, polygenic risk scores (PRS) can be …
[HTML][HTML] Evaluation of polygenic risk scores for prediction of prostate cancer in Korean men
JJ Oh, E Kim, E Woo, SH Song, JK Kim, H Lee… - Frontiers in …, 2020 - frontiersin.org
Aims The purpose of this study is to evaluate an aggregate influence of prostate cancer
(PCa) susceptibility variants on the development of PCa in Korean men by using the …
(PCa) susceptibility variants on the development of PCa in Korean men by using the …
[HTML][HTML] Genetic score is an objective and better measurement of inherited risk of prostate cancer than family history
Positive family history of prostate cancer (PCa) has been consistently associated with
increased PCa risk [1]. It is widely used in clinical practice and is a strong indication …
increased PCa risk [1]. It is widely used in clinical practice and is a strong indication …
Predictive performance of prostate cancer risk in Chinese men using 33 reported prostate cancer risk‐associated SNPs
J Zheng, F Liu, X Lin, X Wang, Q Ding, H Jiang… - The …, 2012 - Wiley Online Library
BACKGROUND Genome‐wide association studies (GWAS) have identified more than 30
single nucleotide polymorphisms (SNPs) that were reproducibly associated with prostate …
single nucleotide polymorphisms (SNPs) that were reproducibly associated with prostate …
[HTML][HTML] Prediction of clinically significant prostate cancer using polygenic risk models in Asians
SH Song, E Kim, E Woo, E Kwon, S Yoon… - … and clinical urology, 2022 - ncbi.nlm.nih.gov
Purpose To develop and evaluate the performance of a polygenic risk score (PRS)
constructed in a Korean male population to predict clinically significant prostate cancer …
constructed in a Korean male population to predict clinically significant prostate cancer …
[HTML][HTML] Prostate cancer risk-associated genetic markers and their potential clinical utility
Prostate cancer (PCa) is one of the most common cancers among men in Western
developed countries and its incidence has increased considerably in many other parts of the …
developed countries and its incidence has increased considerably in many other parts of the …
Validation of a prostate cancer polygenic risk score
Background Genome‐wide association studies have identified over 100 single‐nucleotide
polymorphisms (SNPs) associated with prostate cancer (PrCa), and polygenic risk scores …
polymorphisms (SNPs) associated with prostate cancer (PrCa), and polygenic risk scores …