IFN-α has been shown to induce both antiviral and antiproliferative activities in animals. This
report describes the biological activity of five recently identified feline IFN-α subtypes …

Type I interferons (IFN) are important mediators of the host defense against viral infections in
mammals. In humans multiple subtypes of IFN-α exist, most of which possess antiviral …

Cats are becoming more popular as household companions and pets, forming close
relationships with humans. Although feline viral diseases can pose serious health hazards …

The interferons (IFNs) are a large family of multifunctional secreted protein involved in
antiviral defense, cell growth regulation, and immune activation. The human IFNs are used …

An understanding of the nature of immune protection and the role of immune effector
products such as interferon-γ (IFN-γ) in the control of infectious disease is fundamental to the …

We have analyzed the ability of three molecular clones of feline immunodeficiency virus
(FIV) and an ex vivo variant to infect nine distinct specific-pathogen-free feline cell lines in …

Two kinds of FeIFN-α consisting of 166 amino acids (aa) and 171 aa were expressed in
Escherichia coli, and the purified proteins were tested for antiviral activity on homologous …

Feline calicivirus cause feline respiratory diseases, and inactivated and attenuated vaccines
are available for its prevention. Moreover, the presence of vaccine breakdown strains (VBS) …

Abstract Interferon (IFN)-λs, members of the type III IFN group, were recently identified in
several vertebrates. Although IFN-λs have the potential to be utilized as antiviral and …

A bovine IFN-ε (BoIFN-ε) gene was amplified from bovine liver genomic DNA consisting of a
463 bp partial 5′ UTR, 582 bp complete ORF and 171 bp partial 3′ UTR, which encodes a …