Lung cancer is the most common type of cancer with the highest cancer-associated mortality
rates worldwide, as well as in Vietnam. Numerous studies have demonstrated that higher …

(1) Background: Immune cell therapy recently attracted enormous attention among scientists
as a cancer treatment, but, so far, it has been poorly studied and applied in Vietnam. The …

Background Natural killer (NK) cells can be used as an adoptive immunotherapy to treat
cancer patients. Purpose In this study, we evaluated the efficacy of highly activated NK …

Background Natural killer (NK) cells constantly survey surrounding tissues and remove
newly generated cancer cells, independent of cancer antigen recognition. Although there …

Natural killer (NK) cells can kill a wide range of cancer cells and are a promising tool for cell
therapy of cancer. NK cells cytotoxicity is regulated by a balance between stimulatory and …

Methods PBMCs and HFWT cells were co-cultured to expand NK cells. The cytotoxicity of
NK cells was measured using 51Cr release assay and crystal violet (CV) staining. The …

Preserving the activities of natural killer (NK) cells in human peripheral blood mononuclear
cells (PBMCs) after ex vivo expansion and activation is critical for NK cell-based therapy …

Rat spleen cells with NK activity were enriched by discontinuous percoll density gradient
centrifugation. Morphologically, about 50% were large granular lymphocytes (LGL), and the …

Natural killer (NK) cell therapy has proven to be a promising approach for the treatment of
malignancies. Osaki method for ex-vivo autologous NK cell expansion has been recently …

Aim To obtain sufficient numbers of pure and activated human primary NK cells for potential
clinical application. Methods PBMC based ex vivo expansion of natural killer cells was set …