Compounded brain volume deficits in schizophrenia-alcoholism comorbidity

DH Mathalon, A Pfefferbaum, KO Lim… - Archives of General …, 2003 - jamanetwork.com
Background Schizophrenia and alcoholism are characterized by brain volume
abnormalities. Despite the frequent comorbidity of these conditions, the potentially …

Patterns of regional cortical dysmorphology distinguishing schizophrenia and chronic alcoholism

EV Sullivan, DH Mathalon, KO Lim, L Marsh… - Biological …, 1998 - Elsevier
BACKGROUND:: This study used magnetic resonance imaging (MRI) to compare the extent
and pattern of tissue volume deficit and cerebrospinal fluid volume enlargement in chronic …

Progressive brain volume changes and the clinical course of schizophrenia in men: a longitudinal magnetic resonance imaging study

DH Mathalon, EV Sullivan, KO Lim… - Archives of general …, 2001 - jamanetwork.com
Background We sought to determine whether the brain dysmorphology previously observed
cross-sectionally in people with schizophrenia progresses over time and whether such …

The impact of substance use on brain structure in people at high risk of developing schizophrenia

KA Welch, AM McIntosh, DE Job… - Schizophrenia …, 2011 - academic.oup.com
Ventricular enlargement and reduced prefrontal volume are consistent findings in
schizophrenia. Both are present in first episode subjects and may be detectable before the …

Heterogeneity and homogeneity of regional brain structure in schizophrenia: a meta-analysis

SP Brugger, OD Howes - JAMA psychiatry, 2017 - jamanetwork.com
Importance Schizophrenia is associated with alterations in mean regional brain volumes.
However, it is not known whether the clinical heterogeneity seen in the disorder is reflected …

Effects of alcohol consumption and antipsychotic medication on brain morphology in schizophrenia

R Nesvåg, A Frigessi, EG Jönsson, I Agartz - Schizophrenia research, 2007 - Elsevier
Magnetic resonance imaging (MRI) studies have shown smaller volumes of grey matter
(GM) and white matter (WM) both in schizophrenia and among patients with alcohol abuse …

[HTML][HTML] Severity of schizophrenia and magnetic resonance imaging abnormalities: a comparison of state and veterans hospital patients

L Marsh, KO Lim, AL Hoff, D Harris, M Beal, K Minn… - Biological …, 1999 - Elsevier
Background: The relationship between illness severity and neuroanatomical abnormalities
in schizophrenia remains unclear. The purpose of this study was to test whether the pattern …

MRI brain volume abnormalities in young, nonpsychotic relatives of schizophrenia probands are associated with subsequent prodromal symptoms

BC Ho - Schizophrenia research, 2007 - Elsevier
Schizophrenia is characterized by subtle but well-replicated total and regional (frontal and
temporal) brain tissue volume deficits. Studies of individuals at-risk for developing …

Heritability of changes in brain volume over time in twin pairs discordant for schizophrenia

RGH Brans, NEM van Haren… - Archives of General …, 2008 - jamanetwork.com
Context Structural brain abnormalities have consistently been found in schizophrenia, with
increased familial risk for the disease associated with these abnormalities. Some brain …

Frontal and temporal lobe brain volumes in schizophrenia: relationship to symptoms and clinical subtype

B Turetsky, PE Cowell, RC Gur… - Archives of general …, 1995 - jamanetwork.com
Background: Quantitative magnetic resonance imaging (MRI) studies demonstrate reduced
brain volumes in schizophrenics, but specific structural abnormalities have not been clearly …