Background Peak oxygen uptake (peak VO 2) and its decline predict death or serious
cardiovascular adverse events in patients with Fontan circulation. Our aim was to study VO 2 …

The unique, unphysiological Fontan circulation is associated with an impaired functional
status of the patients that is suggested to deteriorate over time. Unfortunately, previous …

A modified Fontan procedure is performed to palliate single ventricle malformations. This
hemodynamic arrangement sets systemic venous pressure unphysiologically high which …

In patients after Fontan completion exercise capacity is significantly reduced. Although peak
oxygen consumption (VO 2peak) is a strong prognostic factor in many cardiovascular …

Despite improvement in survival, patients with a Fontan circulation are at risk for numerous
complications, and exercise capacity and quality of life are usually reduced compared with …

BACKGROUND: Post-exercise heart rate (HR) and oxygen uptake (V˙ O2) recover more
slowly in patients with the Fontan circulation, but little is known about the determinants of the …

In the pediatric population, exercise capacity differs between females and males and the
gap widens through adolescence. However, specific age-and sex-based changes in …

Over the past five decades, the Fontan operation has evolved as the final palliative
procedure for various forms of single ventricle heart disease. While life expectancy of …

Fontan cohort, in whom maximal exercise effort is often limited. Methods: Fifty-two Fontan
patients received cardiopulmonary exercise tests at least 12 months after Fontan …

Impaired exercise capacity is common after the Fontan procedure and is attributed to
cardiovascular limits. The Fontan circulation, however, is also distinctively vulnerable to …