Influence of hypertension on brain amyloid deposition and Alzheimer's disease signature neurodegeneration
SY Jeon, MS Byun, D Yi, JH Lee, YM Choe, K Ko… - Neurobiology of …, 2019 - Elsevier
This study aimed to investigate the relationship of hypertension with beta-amyloid (Aβ) and
neurodegeneration biomarkers of Alzheimer's disease (AD) and the modulating effect of …
neurodegeneration biomarkers of Alzheimer's disease (AD) and the modulating effect of …
Blood Pressure Level Is Associated With Changes in Plasma Aβ1 –40 and Aβ1–42 Levels: A Cross-sectional Study Conducted in the Suburbs of Xi'an, China
M She, S Shang, N Hu, C Chen, L Dang… - Frontiers in Aging …, 2021 - frontiersin.org
Objectives: Amyloid-β (Aβ) deposition in the brain is the hallmark of Alzheimer's disease
(AD) pathology. Hypertension is a risk factor for AD, but the effects of hypertension on Aβ …
(AD) pathology. Hypertension is a risk factor for AD, but the effects of hypertension on Aβ …
Role of Hypertension in Aggravating Aβ Neuropathology of AD Type and Tau‐MediatedMotor Impairment
C Diaz-Ruiz, J Wang, H Ksiezak-Reding… - Cardiovascular …, 2009 - Wiley Online Library
Epidemiological evidence suggests that hypertension may accelerate the onset and
progression of Alzheimer′ s disease (AD). In this study, we explored the role of …
progression of Alzheimer′ s disease (AD). In this study, we explored the role of …
Cardiovascular risk factors, cortisol, and amyloid-β deposition in Alzheimer's Disease Neuroimaging Initiative
JB Toledo, E Toledo, MW Weiner, CR Jack Jr… - Alzheimer's & …, 2012 - Elsevier
BACKGROUND: There is epidemiological evidence that cardiovascular risk factors (CVRF)
also are risk factors for Alzheimer's disease, but there is limited information on this from …
also are risk factors for Alzheimer's disease, but there is limited information on this from …
Joint effect of hypertension and APOE genotype on CSF biomarkers for Alzheimer's disease
MI Kester, WM Van der Flier, G Mandic… - Journal of …, 2010 - content.iospress.com
We examined the impact of hypertension on cerebrospinal fluid (CSF) biomarkers amyloid-
β1− 42 (Aβ42), total tau (tau), and phosphorylated tau at threonine 181 (ptau-181), and …
β1− 42 (Aβ42), total tau (tau), and phosphorylated tau at threonine 181 (ptau-181), and …
Hypertension is associated with worse cognitive function and hippocampal hypometabolism in Alzheimer's disease
I Moonga, F Niccolini, H Wilson… - European journal of …, 2017 - Wiley Online Library
Background and purpose A growing body of evidence suggests that cardiovascular disease
risk factors including hypertension may be linked to sporadic Alzheimer's disease (AD). It is …
risk factors including hypertension may be linked to sporadic Alzheimer's disease (AD). It is …
Blood pressure is associated with higher brain amyloid burden and lower glucose metabolism in healthy late middle-age persons
JBS Langbaum, K Chen, LJ Launer, AS Fleisher… - Neurobiology of …, 2012 - Elsevier
Epidemiological studies suggest that elevated blood pressure (BP) in midlife is associated
with increased risk of Alzheimer's disease (AD) in late life. In this preliminary study, we …
with increased risk of Alzheimer's disease (AD) in late life. In this preliminary study, we …
Synergistic interaction of high blood pressure and cerebral beta-amyloid on tau pathology
T Kim, D Yi, MS Byun, H Ahn, JH Jung, N Kong… - Alzheimer's research & …, 2022 - Springer
Background Hypertension has been associated with Alzheimer's disease (AD) dementia as
well as vascular dementia. However, the underlying neuropathological changes that link …
well as vascular dementia. However, the underlying neuropathological changes that link …
Systolic blood pressure is associated with increased brain amyloid load in mild cognitively impaired participants: Alzheimer's disease neuroimaging initiatives study
TV Fungwe, JS Ngwa, SP Johnson, JV Turner… - Dementia and geriatric …, 2023 - karger.com
Abstract Background: Cardiovascular disease (CVD), including elevated blood pressure
(BP), is known to promote Alzheimer's disease (AD) risk. Although brain amyloid load is a …
(BP), is known to promote Alzheimer's disease (AD) risk. Although brain amyloid load is a …
Effects of hypertension and anti-hypertensive treatment on amyloid-β (Aβ) plaque load and Aβ-synthesizing and Aβ-degrading enzymes in frontal cortex
Epidemiological data associate hypertension with a predisposition to Alzheimer's disease
(AD), and a number of postmortem and in vivo studies also demonstrate that hypertension …
(AD), and a number of postmortem and in vivo studies also demonstrate that hypertension …