Estrogen receptors alpha (ERα) and beta (ERβ) are nuclear transcription factors that are
involved in the regulation of many complex physiological processes in humans. Modulation …

Today we have to consider the existence of two estrogen receptors, a and b, in our attempts
to understand the role of estrogen receptors in physiology and pathology, and to explain the …

Although the action of estrogens has been traditionally explained by the binding to and
transactivation of the nuclear estrogen receptor (ER) α and ERβ, recently the G protein …

Estrogen mediate its biological effects through its association with estrogen receptors (ERs).
They also regulate the expression of a variety of genes involved in distinct physiological …

The orphan receptor estrogen-related receptor α (ERRα) is a member of the nuclear
receptor superfamily of ligand-regulated transcription factors. This protein is structurally most …

Estrogenic effects are mediated through two estrogen receptor (ER) subtypes, ERα and
ERβ. Estrogens are the most commonly prescribed drugs to treat menopausal conditions …

Estrogen-related receptor (ERR) γ is an orphan nuclear hormone receptor that belongs to
the ERR subfamily of transcription factors. No endogenous ligand has been identified to …

Estrogen-signaling pathways are implicated in the development of breast cancer and
prostate cancer. Various studies have focused on additional signaling pathways, mediated …

Cancer is a major public health issue and represents the second leading cause of death in
women worldwide, as female reproductive-related neoplasms are the main cause of …

Over the decades, our understanding of estrogen receptor (ER) function has evolved. Today
we are confronted by at least two nuclear ERs, ERα and ERβ, and a number of putative …