The physiological role of estrogen in the female endometrium is well established. On the
basis of responses to steroid hormones (progesterone, androgen, and estrogen), the …

Over the past two decades, we have learned that estrogens play important physiological
roles not only in women but also in men and that the biological effects of estrogen are …

Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) belong to a superfamily of
nuclear receptors called steroid hormone receptors, which, upon binding ligand, dimerize …

The estrogen receptors ERα and ERβ are the main mediators of estrogen action and
estrogens play an important role in a variety of aspects of physiology besides their well …

Estrogens, acting on both estrogen receptors alpha (ERalpha) and beta (ERbeta) are
recognized as important regulators of glucose homeostasis and lipid metabolism. ERs …

Estrogen receptor α (ERα) is closely associated with both hormone-dependent and hormone-
independent tumors, and it is also essential for the development of these cancers. The …

Estrogens play a fundamental role in the development and normal physiological function of
multiple tissue systems and have been implicated in the ontogeny of cancers. The biological …

Estrogen is involved in numerous physiological and pathophysiological systems. Its role in
driving estrogen receptor-expressing breast cancers is well established, but it also has …

Estrogens, acting through its two receptors, ESR1 (hereafter designated ER alpha) and
ESR2 (hereafter designated ER beta), have diverse physiological effects in the reproductive …

By regulating activities and expression levels of key signaling molecules, estrogens control
mechanisms that are responsible for crucial cellular functions. Ligand binding to estrogen …