The discovery of estrogen receptor-β (ERβ) in 1996 stimulated great interest in the
physiological roles and molecular mechanisms of ERβ action. We now know that ERβ plays …

The estrogen receptor (ER) has functionality in selected ovarian cancer subtypes and
represents a potential target for therapy. The majority (> 80%) of high grade serous, low …

Estrogens have been related to energy balance and glucose metabolism for a long time;
however, the mechanisms involved in their actions are now being unveiled. The …

The estrogen receptors ERR and ERβ are ligand-regulated transcription factors and also
initiators of extranuclear signaling cascades in target cells. As such, they function as …

The discovery of the second estrogen receptor (ER) in 1995 surprised many
endocrinologists and resulted in some scepticism regarding its physiological importance …

We previously showed that (a) estrogen-related receptor α1 (ERRα1) down-modulates
estrogen receptor (ER)–stimulated transcription in low ErbB2–expressing MCF-7 mammary …

The discovery of ERβ in the middle of the 1990s represents a paradigm shift in our
understanding of estrogen signaling. It has turned out that estrogen action is not mediated …

Central Nervous System and the Hypothalamo-Pituitary Axis: Estrogens are reported to
influence a variety of functions in the central nervous system (CNS) such as learning …