Impact of different approaches to calculation of treatment activities on achieved doses in radioiodine therapy of benign thyroid diseases

J Hammes, L van Heek, M Hohberg, M Reifegerst… - EJNMMI physics, 2018 - Springer
Purpose Radioiodine has been used for the treatment of benign thyroid diseases for over 70
years. However, internationally, there is no common standard for pretherapeutic dosimetry to …

Treatment of hyperthyroidism with radioiodine targeted activity: a comparison between two dosimetric methods

E Amato, A Campennì, S Leotta, RM Ruggeri, S Baldari - Physica Medica, 2016 - Elsevier
Radioiodine therapy is an effective and safe treatment of hyperthyroidism due to Graves'
disease, toxic adenoma, toxic multinodular goiter. We compared the outcomes of a …

Radioiodine therapy of benign thyroid disorders: what are the effective thyroidal half-life and uptake of 131I?

C Kobe, W Eschner, M Wild, I Rahlff… - Nuclear medicine …, 2010 - journals.lww.com
Aim The use of radioiodine therapy is common in the treatment of benign thyroid disease.
Council directive Euratom 97/43 requires that for all medical exposure of individuals for …

A NTCP approach for estimating the outcome in radioiodine treatment of hyperthyroidism

L Strigari, R Sciuto, M Benassi, S Bergomi… - Medical …, 2008 - Wiley Online Library
Radioiodine has been in use for over as a treatment for hyperthyroidism. Major changes in
clinical practice have led to accurate dosimetry capable of avoiding the risks of adverse …

Accuracy and optimal timing of activity measurements in estimating the absorbed dose of radioiodine in the treatment of Graves' disease

S Merrill, J Horowitz, AC Traino… - Physics in Medicine …, 2011 - iopscience.iop.org
Calculation of the therapeutic activity of radioiodine 131 I for individualized dosimetry in the
treatment of Graves' disease requires an accurate estimate of the thyroid absorbed radiation …

A dosimetric approach to patient‐specific radioiodine treatment of Graves' disease with incorporation of treatment‐induced changes in thyroid mass

AC Traino, F Di Martino, M Lazzeri - Medical physics, 2004 - Wiley Online Library
The traditional algorithms (Marinelli–Quimby and MIRD) used for the absorbed dose
calculation in radionuclide therapy generally assume that the mass of the target organs does …

Graves' disease radioiodine‐therapy: Choosing target absorbed doses for therapy planning

J Willegaignon, MT Sapienza, GB Coura‐Filho… - Medical …, 2014 - Wiley Online Library
Purpose: The precise determination of organ mass (mth) and total number of disintegrations
within the thyroid gland () are essential for thyroid absorbed‐dose calculations for …

Improving individualised dosimetry in radioiodine therapy for hyperthyroidism using population biokinetic modelling

JM Pérez, AO Salas, YS Guardiola, JCA Callejo - Physica Medica, 2019 - Elsevier
The application of an individualised dosimetric procedure for radioiodine therapy requires
the intensive use of resources in nuclear medicine facilities. In practice, the amount of data …

Optimized radioiodine therapy for Graves' disease: two MIRD-based models for the computation of patient-specific therapeutic 131I activity

T Carlier, PY Salaun, MB Cavarec… - Nuclear medicine …, 2006 - journals.lww.com
Aim 131 I therapy is increasingly used for Graves' hyperthyroidism. Debate remains about
the best method for calculating the activity to administer, as well as about the potential …

Radioiodine therapy of benign thyroid-disorders

T Hartmann, W Vach, L Frings, M Mix… - Nuklearmedizin …, 2017 - thieme-connect.com
Aim: In radioiodine therapy (RIT) of benign thyroid-disorders empirical half-lives (HL emp)
may be used to calculate therapeutic dose. In this study the effective half-life (HLf as well as …