Stress robustness by definition, incorporates both stress resistance (organisms endure
greater stressor intensity or duration before suffering negative consequences) and stress …

The brain is the central organ of stress and adaptation to stress because it perceives and
determines what is threatening, as well as the behavioral and physiological responses to the …

The understanding of the mechanisms whereby energy balance is regulated is essential to
the unraveling of the pathophysiology of obesity. In the last three decades, focus was put on …

Featured Articles : Neuroscience Gateway Page 1 Microglia from LPS-treated Cx3cr1-/- mice (b)
showed increased activation relative to microglia from LPS-treated Cx3cr1+/mice (a) …

BACKGROUND Stress is necessary for animals including humans to adapt their behaviors
and physiology to changes in both the internal and external environment. However, Such …

Fractalkine is a neuronally expressed chemokine that acts through its G‐protein‐coupled
receptor CX3CR1, localized on microglial and immune cells. Fractalkine might be involved …

Microglia, the resident macrophage cells of the central nervous system (CNS), are involved
in a myriad of processes required to maintain CNS homeostasis. These cells are dynamic …

The chemokine fractalkine primarily involves in chemotaxis, adherence and inflammation.
Recently it has been discovered owning the ability of inhibiting cell death in neurons and …

Stressful life events impact on brain and bodily function and represent major risk factors for
stress-related neuropsychiatric disorders. The response to stressful events can promote …

Abstract CXCL12/SDF-1α and CX3CL1/fractalkine are constitutively expressed in the brain,
which indicates their significant functions. Emerging evidence highlights the role of …