Cognitive stimulation has been proposed as a non-pharmacological intervention to be used
in primary, secondary and tertiary prevention approaches for Alzheimer's disease. A …

Introduction: Among the risk factors identified in the sporadic forms of Alzheimer's disease
(AD), environmental and lifestyle elements are of growing interest. Clinical observations …

Lack of physical activity (PA) is a risk factor for Alzheimer's disease (AD), and PA
interventions are believed to provide an effective non-pharmacological approach for …

A lifestyle rich in physical and mental activities protects against Alzheimer's disease (AD) but
the underlying mechanisms are unclear. We have proposed that this is mediated by a stress …

Although it is generally accepted that Aβ contributes to the pathogenesis of Alzheimer's
disease (AD), other factors that impact the severity and time of onset of the disease are not …

Stress responses are essential for survival, but become detrimental to health and cognition
with chronic activation. Chronic hypothalamic-pituitary-adrenal axis release of …

Lifestyle factors emerge as key modifiers of the risk and progression of Alzheimer's disease
(AD), the most prevalent senile dementia. Stress accelerates, whereas positive lifestyle …

An important factor that may affect the severity and time of onset of Alzheimer's disease (AD)
is chronic stress. Epidemiological studies report that chronically stressed individuals are at …

Recent clinical data have implicated chronic adverse stress as a potential risk factor in the
development of Alzheimer's disease (AD) and data also suggest that normal, physiological …

Oxidative stress is a key feature during progression of chronic neurodegenerative conditions
such as Alzheimer's disease. In aging humans and animals, voluntary exercise lowers …