To discuss and evaluate new technologies for a better diagnosis of corneal diseases and
limbal stem cell deficiency, the outcomes of a consensus process within the European …

The future of eye reconstruction invariably includes stem cells transplantation. Corneal
limbus, corneal stroma, trabeculum, retinal cells, optic nerve, and all structures that are …

Corneal failure is a highly prevalent cause of blindness. One special cause of corneal failure
occurs due to malfunction or destruction of the limbal stem cell niche, upon which the …

Stem cells are the ultimate source of the rapidly self-renewing corneal epithelium and are
located in the basal layer of the limbal epithelium. Ocular surface defense mechanisms are …

The limbus is the anatomical and functional barrier between the corneal and conjunctival
epithelia. It is characterized by the presence of the limbal stem cell niche, which allows …

The function of limbal stem/progenitor cells (LSCs) is critical to maintain corneal epithelial
homeostasis. Many external insults and intrinsic defects can be deleterious to LSCs and …

Limbal stem cell deficiency is predominantly caused by severe eye burns resulting in a
decreased or a complete ablation of the regenerative potential of these stem cells. The …

Limbal stem cell deficiency (LSCD) can cause significant corneal vascularization and
scarring and often results in serious visual morbidity. An early and accurate diagnosis can …

Efforts to develop and improve techniques for diagnosing LSCD are ongoing. Increased
knowledge of limbal stem cells and components of their niches may not only help in …

The corneal limbus harbors corneal epithelial stem cells and contributes to the unique
microenvironment of the stem cell niche. Corneal conditions, such as infections, tumors …