The β chain of the interferon-γ receptor (IFNGR-2) plays a critical role in signal transmission
to the nucleus by IFN-γ. Here, we cloned the full-length cDNA of IFNGR-2 of Huiyang …

Abstract Interferon (IFN)-λs, members of the type III IFN group, were recently identified in
several vertebrates. Although IFN-λs have the potential to be utilized as antiviral and …

Interferon regulatory factors (IRFs) play a key role in many aspects of immune response, and
IRF1, IRF3, and IRF7 are positive regulators of IFN induction in mammals. However, IRF3 …

Type I interferons (IFN) are important mediators of the host defence against viruses through
binding to the cell surface receptors, among which the binding to type I IFN receptor 2 …

IFN-λ1 is a member of a new family of interferons called type Ⅲ IFNs with similar functions to
type ⅠIFNs. Previously we obtained recombinant soluble human rhIFN-λ1 from Pichia …

Abstract Interferon-epsilon (IFN-ε) is a type I IFN playing an essential role in innate and
adaptive immunity against viral infection. Ovis aries IFN-ε (OvIFN-ε), consisting of 582 bp …

Abstract The type IV IFN (IFN-υ) is reported in vertebrates from fish to primary mammals with
IFN-υR1 and IL-10R2 as receptor subunits. In this study, the proximal promoter of IFN-υ was …

Interferon-gamma (IFN-gamma) possesses potent immunostimulatory properties, and it has
recently been shown to have potential therapeutic properties. Recombinant protein …

Interferons (IFNs) have been known as antiviral genes and they are classified by type 1, type
2, and type 3 IFN. The type 1 IFN consists of IFNα, IFNβ, IFNτ, and IFNω whereas the type 2 …

The expression, purification, detection, and assay of recombinant proteins have been made
more convenient and rapid by the use of small affinity tags. To facilitate the purification of …