ABSTRACT Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous and
complex disease with great morbidity and mortality. Despite the new developments in the …

The new Global Initiative for Chronic Obstructive Lung Disease update has moved the
principles of treatment of stable chronic obstructive pulmonary disease (COPD) forward by …

The study of airway diseases continues to present several challenges for modern medicine.
The different disease presentations with variables and overlapping features may result in a …

Highlights•Several phenotypes characterize chronic obstructive pulmonary disease
(COPD).•Response to pharmacological treatment in COPD is highly variable.•Guidelines …

The complexity of COPD implies the need to identify groups of patients with similar clinical
characteristics and prognosis or treatment requirements. This is why much attention has …

Abstract Chronic Obstructive Pulmonary Disease (COPD) phenotypes have become
increasingly recognized as important for grouping patients with similar presentation and/or …

Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease,
and there is a clinical need for validated markers and biomarkers that can contribute to the …

For decades, chronic obstructive pulmonary disease (COPD) has been considered a
relentlessly progressive disease in which the deterioration of lung function is associated with …

Introduction: Treatment recommendations are based on randomized controlled trials (RCTs).
However, only about 1 in 20 people meet the inclusion criteria for RCTs forming consensus …

Abstract Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous and
multisystemic disease with progressive increasing morbidity and mortality. COPD is now …