Vascular abnormalities: The insidious pathogenesis of Alzheimer's disease☆

J Shi, G Perry, MA Smith, RP Friedland - Neurobiology of Aging, 2000 - Elsevier
Alzheimer's disease (AD) and cerebrovascular dementia (CVD) are two major causes of
senile dementia in elderly individuals. Mounting evidence from epidemiological, clinical, and …

Overlap between pathology of Alzheimer disease and vascular dementia

RN Kalaria, C Ballard - Alzheimer Disease & Associated …, 1999 - journals.lww.com
There is overwhelming evidence to suggest that the neuropathology of Alzheimer disease
(AD) extends beyond amyloid plaques and neurofibrillary tangles. Review of various …

Is the distinction between Alzheimer's disease and vascular dementia possible and relevant?

R Ravona-Springer, M Davidson… - Dialogues in clinical …, 2003 - Taylor & Francis
Advances in epidemiological, clinical, imaging, and neuropathological studies have
undermined the clear distinction between vascular and Alzheimer-type dementia, which has …

Alzheimer's Disease and Vascular Aging: JACC Focus Seminar

M Cortes-Canteli, C Iadecola - Journal of the American College of …, 2020 - jacc.org
Alzheimer's disease, the leading cause of dementia in the elderly, is a neurodegenerative
condition characterized by accumulation of amyloid plaques and neurofibrillary tangles in …

Cerebrovascular and cardiovascular pathology in Alzheimer's disease

JC de la Torre - International Review of Neurobiology, 2009 - Elsevier
Presently, compelling evidence indicates that Alzheimer's disease (AD) is a vascular
disorder with neurodegenerative consequences and should be treated as such. A …

Vascular disease and dementias: paradigm shifts to drive research in new directions

MA Kling, JQ Trojanowski, DA Wolk, VMY Lee… - Alzheimer's & …, 2013 - Elsevier
Vascular disease was once considered the principal cause of aging-related dementia. More
recently, however, research emphasis has shifted to studies of progressive …

Atherosclerotic risk factors, vascular cognitive impairment, and Alzheimer disease

JC Kovacic, V Fuster - Mount Sinai Journal of Medicine: A …, 2012 - Wiley Online Library
The involvement of vascular factors in Alzheimer dementia was first appreciated over 100
years ago. Recently, significant advances in our understanding of these brain‐vascular …

[HTML][HTML] Pathophysiologic relationship between Alzheimer's disease, cerebrovascular disease, and cardiovascular risk: a review and synthesis

CY Santos, PJ Snyder, WC Wu, M Zhang… - Alzheimer's & Dementia …, 2017 - Elsevier
As the population ages due to demographic trends and gains in life expectancy, the
incidence and prevalence of dementia increases, and the need to understand the etiology …

The role of cardiovascular risk factors in Alzheimer's disease

R Ravona-Springer, M Davidson, S Noy - Cns Spectrums, 2003 - cambridge.org
The distinction between Alzheimer's disease and vascular dementia, the two most common
types of dementia, has been undermined by recent advances in epidemiologic, clinical …

Vascular risk factors and Alzheimer's disease

JT O'Brien, HS Markus - BMC medicine, 2014 - Springer
Vascular factors are now established risk factors for cognitive decline, both for dementia and
its two main subtypes: Alzheimer's disease (AD) and vascular dementia. Their impact likely …