The unique immunological features of heparin‐induced thrombocytopenia
P Staibano, DM Arnold… - British Journal of …, 2017 - Wiley Online Library
Heparin‐induced thrombocytopenia (HIT) is a serious drug reaction that leads to a decrease
in platelet count and a high risk of thrombosis. HIT patients produce pathogenic …
in platelet count and a high risk of thrombosis. HIT patients produce pathogenic …
Evolving concepts of pathogenesis of heparin‐induced thrombocytopenia: diagnostic and therapeutic implications
BH Chong - International Journal of Laboratory Hematology, 2020 - Wiley Online Library
Heparin‐induced thrombocytopenia (HIT) is an immune reaction to heparin. It often causes
severe thrombosis which may lead to limb gangrene and thrombosis‐associated death. The …
severe thrombosis which may lead to limb gangrene and thrombosis‐associated death. The …
The biological basis of immune heparin-induced thrombocytopenia.
J Amiral, A Marfaing-Koka, M Poncz, D Meyer - Platelets, 1998 - europepmc.org
Heparin induced thrombocytopenia (HIT) remains the most severe adverse effect of heparin
therapy. Recently, new information has been uncovered regarding the pathogenesis of this …
therapy. Recently, new information has been uncovered regarding the pathogenesis of this …
Pathophysiology and laboratory testing of heparin-induced thrombocytopenia.
BH Chong, M Eisbacher - Seminars in hematology, 1998 - europepmc.org
Heparin-induced thrombocytopenia (HIT) type II is an immune-mediated reaction that
generally occurs 5 to 14 days after initiation of heparin therapy. It is characterized by a …
generally occurs 5 to 14 days after initiation of heparin therapy. It is characterized by a …
[PDF][PDF] Heparin-induced thrombocytopenia: pathophysiology and new treatment options
J Harenberg, I Jörg, T Fenyvesi - Pathophysiology of haemostasis and …, 2002 - karger.com
Heparin induced thrombocytopenia (HIT) is a severe complication of heparin therapy. It is
generally accompanied by a paradoxical decrease in platelets leading to activation of …
generally accompanied by a paradoxical decrease in platelets leading to activation of …
Insights into heparin‐induced thrombocytopenia
GP Anderson - British journal of haematology, 1992 - Wiley Online Library
Heparin‐induced thrombocytopenia (HIT) is characterized by the presence of an antibody
which can activate platelets in the presence of heparin. The in vitro Ca2+ mobilization …
which can activate platelets in the presence of heparin. The in vitro Ca2+ mobilization …
Heparin-induced thrombocytopenia: clinical considerations of alternative anticoagulation with various glycosaminoglycans and thrombin inhibitors
S Haas, JM Walenga, WP Jeske… - Clinical and Applied …, 1999 - journals.sagepub.com
Heparin-induced thrombocytopenia (HIT), the most common complication of heparin
therapy, is also the most common form of the drug-induced thrombocytopenias. HIT is …
therapy, is also the most common form of the drug-induced thrombocytopenias. HIT is …
Heparin-induced thrombocytopenia: when a low platelet count is a mandate for anticoagulation
TL Ortel - ASH Education Program Book, 2009 - ashpublications.org
Heparin-induced thrombocytopenia (HIT) is an immune-mediated disorder caused by the
development of antibodies to platelet factor 4 (PF4) and heparin. The thrombocytopenia is …
development of antibodies to platelet factor 4 (PF4) and heparin. The thrombocytopenia is …
Heparin-induced thrombocytopenia: an overview
JG Kelton - Blood reviews, 2002 - Elsevier
Heparin-induced thrombocytopenia (HIT) is the most important immunological drug reaction
that patients face today. HIT typically develops in patients 5 days after starting heparin …
that patients face today. HIT typically develops in patients 5 days after starting heparin …
Heparin-induced thrombocytopenia: what clinicians need to know
BH Chong, A Isaacs - Thrombosis and haemostasis, 2009 - thieme-connect.com
In the past two decades there has been significant improvement in its diagnosis and
treatment (1, 4). HIT is a hypersensitivity reaction to unfractionated heparin (UFH) and low …
treatment (1, 4). HIT is a hypersensitivity reaction to unfractionated heparin (UFH) and low …