Shared functional impairment in the prefrontal cortex affects symptom severity across psychiatric disorders
Background The prefrontal deficits in psychiatric disorders have been investigated using
functional neuroimaging tools; however, no studies have tested the related characteristics …
functional neuroimaging tools; however, no studies have tested the related characteristics …
Association of dorsolateral prefrontal cortex dysfunction with disrupted coordinated brain activity in schizophrenia: relationship with impaired cognition, behavioral …
Objective: Although deficits in cognitive control are thought to contribute to the diverse
cognitive and behavioral abnormalities in individuals with schizophrenia, the neural …
cognitive and behavioral abnormalities in individuals with schizophrenia, the neural …
Prefrontal cortex activation during verbal fluency task and tower of London task in schizophrenia and major depressive disorder
Y Xiang, Y Li, C Shu, Z Liu, H Wang, G Wang - Frontiers in Psychiatry, 2021 - frontiersin.org
Background: Cognitive dysfunction is a common clinical feature of mental disorders. A
number of functional near-infrared spectroscopy (fNIRS) studies have shown reduced …
number of functional near-infrared spectroscopy (fNIRS) studies have shown reduced …
Impact of familial loading on prefrontal activation in major psychiatric disorders: a near-infrared spectroscopy (NIRS) study
K Ohi, T Shimada, H Kihara, T Yasuyama, K Sawai… - Scientific reports, 2017 - nature.com
Family history (FH) is predictive of the development of major psychiatric disorders (PSY).
Familial psychiatric disorders are largely a consequence of genetic factors and typically …
Familial psychiatric disorders are largely a consequence of genetic factors and typically …
Impaired prefrontal-basal ganglia functional connectivity and substantia nigra hyperactivity in schizophrenia
BACKGROUND: The theory that prefrontal cortex (PFC) dysfunction in schizophrenia leads
to excess subcortical dopamine has generated widespread interest because it provides a …
to excess subcortical dopamine has generated widespread interest because it provides a …
Imaging frontostriatal function in ultra-high-risk, early, and chronic schizophrenia during executive processing
RA Morey, S Inan, TV Mitchell… - Archives of general …, 2005 - jamanetwork.com
Context Individuals experiencing prodromal symptoms of schizophrenia (ultra-high-risk
group) demonstrate impaired performance on tasks of executive function, attention, and …
group) demonstrate impaired performance on tasks of executive function, attention, and …
Reduced but broader prefrontal activity in patients with schizophrenia during n-back working memory tasks: a multi-channel near-infrared spectroscopy study
Background Caudal regions of the prefrontal cortex, including the dorsolateral (DLPFC) and
ventrolateral (VLPFC) prefrontal cortex, are involved in essential cognitive functions such as …
ventrolateral (VLPFC) prefrontal cortex, are involved in essential cognitive functions such as …
Enhanced prefrontal regional homogeneity and its correlations with cognitive dysfunction/psychopathology in patients with first-diagnosed and drug-naive …
S Gao, Y Ming, J Wang, Y Gu, S Ni, S Lu… - Frontiers in …, 2020 - frontiersin.org
Background: Schizophrenia, regarded as a neurodevelopmental disorder, is characterized
by positive symptoms, negative symptoms, and cognitive dysfunction. Investigating the …
by positive symptoms, negative symptoms, and cognitive dysfunction. Investigating the …
Prefrontal brain network connectivity indicates degree of both schizophrenia risk and cognitive dysfunction
Objective: Cognitive dysfunction is a core feature of schizophrenia, and persons at risk for
schizophrenia may show subtle deficits in attention and working memory. In this study, we …
schizophrenia may show subtle deficits in attention and working memory. In this study, we …
Association of cerebral deficits with clinical symptoms in antipsychotic-naive first-episode schizophrenia: an optimized voxel-based morphometry and resting state …
S Lui, W Deng, X Huang, L Jiang, X Ma… - American Journal of …, 2009 - Am Psychiatric Assoc
Objective: The purpose of the present study was to characterize the association between
clinical symptoms and anatomical and functional cerebral deficits in a relatively large …
clinical symptoms and anatomical and functional cerebral deficits in a relatively large …