Pulmonary responses following quercetin administration in rats after intratracheal instillation of amiodarone

VO Oka, UE Okon, EE Osim - Nigerian Journal of Physiological Sciences, 2019 - ajol.info
Amiodarone, a drug that treats arrhythmias induces pulmonary toxicity through interplay
between oxidative stress and inflammation. Quercetin, a flavonoid widely occurring in …

Effect of long-term administration of amiodarone on rat lung and the possible protective role of vitamin E: a histological and immunohistochemical study

RA Zidan - Egyptian Journal of Histology, 2011 - journals.lww.com
Objective This study was undertaken to investigate the effect of long-term amiodarone
administration and withdrawal on the histological structure of rat lung. In addition, the …

[PDF][PDF] Influence of quercetin on amiodarone pharmacokinetics and biodistribution in rats.

E Ahmad, M Jahangir, NI Bukhari, J Khan… - European Review for …, 2023 - researchgate.net
OBJECTIVE: Amiodarone (AMD), a drug of choice to treat cardiac arrhythmias, has a narrow
therapeutic index (NTI). It inhibits CYP3A4, CYP2C9, and CYP2D6 enzymes. Quercetin …

Protective role of white cabbage extract against amiodarone-induced lung damage in rats

E Ak, İB Turkyilmaz, A Muhan… - Online Turkish Journal of …, 2022 - dergipark.org.tr
Objective: It was intended to study the protective roles of white cabbage on amiodarone
induced lung damage. Materials and Methods: Rats were distributed into 4 groups, Control …

[HTML][HTML] A Comparative Study of Lung-Protective Effects of Melatonin Versus Curcumin in Amiodarone Treated Adult Male Albino Rats

NE Refaay, NM Halloull… - Biomedical and …, 2023 - biomedpharmajournal.org
Amiodarone (AMR) is a very powerful and efficient anti-arrhythmic agent since it outperforms
other treatments in preventing and treating ventricular and supraventricular dysrhythmias …

[PDF][PDF] The possible ameliorative effect of selenium and vitamins combination against amiodarone-induced alveolar damage in albino rat: histological and …

AA Mahdy - J Am Sci, 2014 - researchgate.net
Background: Chronic interstitial pneumonitis is the most common presentation of
amiodarone-induced pulmonary disease. Aim of the work: To throw a light on the damage of …

Ameliorative effect of grape seed and ginkgo biloba against pulmonary damage induced by amiodarone in male albino rats

SR Galaly, M Abdul-Hamid, H Mahmoud… - Journal of Advanced …, 2018 - japer.in
Amiodarone being an orally effective antiarrhythmic drug widely used throughout the world,
had long-term administration side effects such as pulmonary toxicity. Thirty six male albino …

[HTML][HTML] Effect of Aronia melanocarpa fruit juice on amiodarone-induced pneumotoxicity in rats

S Valcheva-Kuzmanova, G Stavreva… - Pharmacognosy …, 2014 - ncbi.nlm.nih.gov
Background: The fruits of Aronia melanocarpa (Michx.) Elliot is extremely rich in biologically
active polyphenols. Objective: We studied the protective effect of A. melanocarpa fruit juice …

Oxidative stress in amiodarone-induced pulmonary toxicity in rats and the protective effect of L-carnitine and vitamin C

D Ahmed, MY Youssef, NM Emam - Mansoura Journal of Forensic …, 2020 - journals.ekb.eg
This study aims to investigate the oxidative stress role in the pathogenesis of amiodarone-
induced pulmonary toxicity and to show whether antioxidants coadministration with …

[PDF][PDF] Amelioration of amiodarone-induced lung fibrosis in rats by grape seed extract

NK Madkour, M Ahmed - J Appl Sci Res, 2013 - researchgate.net
Amiodarone (AM) hydrochloride is indicated for the treatment of serious cardiac arrhythmias.
Unfortunately it is associated with pulmonary toxicity, sometimes with fatal sequelae. The …