Efficacy and tolerability of nebivolol compared with other antihypertensive drugs: a meta-analysis

LM Van Bortel, F Fici, F Mascagni - American Journal of Cardiovascular …, 2008 - Springer
Background and objective Lowering BP to normal levels without quality of life deterioration
is the most important means of reducing cardiovascular risk. Recent studies have …

Protective actions of nebivolol on chronic nitric oxide synthase inhibition-induced hypertension and chronic kidney disease in the rat: a comparison with angiotensin II …

NC Moningka, T Tsarova, JM Sasser… - Nephrology Dialysis …, 2012 - academic.oup.com
Background. Nitric oxide (NO) deficiency contributes to chronic kidney disease (CKD)
progression and hypertension. The β-blocker, nebivolol (N), also enhances NO production …

Nebivolol Ameliorates Nitric Oxide–Deficient Hypertension

LA Fortepiani, MC Ortíz, NM Atucha… - The Scientific World …, 2002 - Wiley Online Library
Nebivolol is a new selective beta 1‐adrenoceptor antagonist with nitric oxide (NO)–
releasing properties. In the present study we have analyzed whether nebivolol affects the …

[PDF][PDF] Nebivolol-pharmacological aspects

GN Sahana, N Sarala, TN Kumar - Int J Biol Med Res, 2011 - Citeseer
Nebivolol is a beta blocker with a unique function which distinguishes it from other beta
blockers. It increases the release of nitric oxide (NO) which produces vasodilatation and …

Clinical pharmacokinetics of nebivolol: a systematic review

N Hanif, A Zamir, I Imran, H Saeed… - Drug Metabolism …, 2023 - Taylor & Francis
Nebivolol is a beta-1 receptor blocker used to treat hypertension, heart failure, erectile
dysfunction, vascular disease, and diabetes mellitus. This review investigated the data …

Nebivolol: new therapy update

SS Sule, W Frishman - Cardiology in review, 2006 - journals.lww.com
Nebivolol is a β-blocker under US Food and Drug Administration review for the treatment of
hypertension. The unique pharmacologic properties of nebivolol include high specificity for …

[HTML][HTML] The favorable kinetics and balance of nebivolol-stimulated nitric oxide and peroxynitrite release in human endothelial cells

RP Mason, RF Jacob, JJ Corbalan, D Szczesny… - BMC Pharmacology and …, 2013 - Springer
Background Nebivolol is a third-generation beta-blocker used to treat hypertension. The
vasodilation properties of nebivolol have been attributed to nitric oxide (NO) release …

[PDF][PDF] Efficacy, tolerability and safety of nebivolol in patients with hypertension and diabetes: a post-marketing surveillance study

LM Van Bortel - Eur Rev Med Pharmacol Sci, 2010 - europeanreview.org
Background and Objectives: Hypertension is a widely prevalent con-dition of elevated blood
pressure (BP) and is the leading risk factor for the development of cardiovascular disease …

Nebivolol: a beta blocker with vasodilator properties

B Waeber - Praxis, 2000 - europepmc.org
Nebivolol is a new cardioselective beta-blocking agent possessing vasodilatory properties
involving the endothelium. This compound is a dl-racemic mixture. The d-enantiomer is …

Nebivolol decreases oxidative stress in essential hypertensive patients and increases nitric oxide by reducing its oxidative inactivation

AF Pasini, U Garbin, MC Nava, C Stranieri… - Journal of …, 2005 - journals.lww.com
Objective To obtain further insight into the mechanism underlying the vasodilator effect of
nebivolol. Since oxidative inactivation of nitric oxide (NO) is regarded as an important cause …