Short-term treatment with a beta-blocker with vasodilative capacities improves intrarenal endothelial function in experimental renal failure
S Gschwend, MB Haug, M Nierhaus, A Schulz, R Vetter… - Life sciences, 2009 - Elsevier
AIMS: In patients with renal disease the cardiovascular risk is greatly increased, and
endothelial dysfunction is assumed to play a pivotal role in this process. Therefore we …
endothelial dysfunction is assumed to play a pivotal role in this process. Therefore we …
Effect of nebivolol on endothelial nitric oxide and peroxynitrite release in hypertensive animals: role of antioxidant activity
RP Mason, R Kubant, RF Jacob… - Journal of …, 2006 - journals.lww.com
We tested the activity of nebivolol, a β 1-selective blocker with respect to nitric oxide (NO)
and peroxynitrite (ONOO−) generation in the endothelium of normotensive Wistar Kyoto …
and peroxynitrite (ONOO−) generation in the endothelium of normotensive Wistar Kyoto …
Preventive effect of nebivolol on contrast-induced nephropathy in rats
Background. Altered renal vasodilatation and oxidative stress are important mechanisms of
contrast-induced nephropathy (CIN). The aim of the present study was to assess the effect of …
contrast-induced nephropathy (CIN). The aim of the present study was to assess the effect of …
Effects of nebivolol versus other antihypertensive drugs on the endothelial dysfunction in patients with essential hypertension
B Li, Q Zhang, H Zhang, C Wang, R Xiu - Bioscience Reports, 2020 - portlandpress.com
We aim to determine whether nebivolol has a better effect on endothelial dysfunction
compared with other β-blockers or other classes of antihypertensive drugs. Searches of the …
compared with other β-blockers or other classes of antihypertensive drugs. Searches of the …
Characterization of nitric oxide release by nebivolol and its metabolites
A Maffei, C Vecchione, A Aretini… - American journal of …, 2006 - academic.oup.com
Background: Nebivolol is a selective β1-adrenergic receptor antagonist that causes a direct
vasodilator effect attributed to the action on vascular nitric oxide (NO). This study aimed to …
vasodilator effect attributed to the action on vascular nitric oxide (NO). This study aimed to …
A Randomized, Double‐Blind, Placebo‐Controlled Parallel‐Group Study to Assess the Efficacy and Safety of Nebivolol, a Novel β‐Blocker, in Patients With Mild to …
RJ Weiss, MA Weber, AA Carr… - The Journal of Clinical …, 2007 - Wiley Online Library
This double‐blind, multicenter, randomized placebo‐controlled study evaluated the
antihypertensive efficacy and safety of nebivolol, a selective β1‐adrenoreceptor blocker with …
antihypertensive efficacy and safety of nebivolol, a selective β1‐adrenoreceptor blocker with …
Case study: the link between hypertension and diabetes
GL Bakris, ER Gonzalez - Journal of Managed Care Pharmacy, 2007 - jmcp.org
BACKGROUND: Many diabetics develop hypertension, and it is a major risk factor for
cardiovascular and microvascular complications. OBJECTIVE: To review a case study of a …
cardiovascular and microvascular complications. OBJECTIVE: To review a case study of a …
Nebivolol in the management of essential hypertension: a review
W McNeely, KL Goa - Drugs, 1999 - Springer
Nebivolol is a lipophilic β 1-blocker. It is devoid of intrinsic sympathomimetic or membrane
stabilising activity but appears to have nitric oxide-mediated vasodilatory effects. Nebivolol is …
stabilising activity but appears to have nitric oxide-mediated vasodilatory effects. Nebivolol is …
The role of nitric oxide in improving endothelial function and cardiovascular health: focus on nebivolol
GL Bakris, JN Basile, TD Giles, AA Taylor - The American journal of …, 2010 - Elsevier
Although β-blockers have been endorsed by guidelines committees for the treatment of
patients with hypertension, particularly those with significant CVD and high CVD risk, there …
patients with hypertension, particularly those with significant CVD and high CVD risk, there …
Quality of life and efficacy of nebivolol in an open-label study in hypertensive patients. the QoLaN study
MP Hermans, O De Coster, L Seidel, A Albert… - Blood …, 2009 - Taylor & Francis
Background. Nebivolol is a highly selective β1-adrenoreceptor antagonist with vasodilating
properties. This study investigated its effect on quality of life (QoL) and blood pressure (BP) …
properties. This study investigated its effect on quality of life (QoL) and blood pressure (BP) …