[HTML][HTML] Porphyromonas gingivalis FimA and Mfa1 fimbriae: Current insights on localization, function, biogenesis, and genotype

Y Hasegawa, K Nagano - Japanese Dental Science Review, 2021 - Elsevier
In general, the periodontal pathogen Porphyromonas gingivalis expresses distinct FimA and
Mfa1 fimbriae. Each of these consists of five FimA–E and five Mfa1–5 proteins encoded by …

[HTML][HTML] Porphyromonas gingivalis FimA fimbriae: Roles of the fim gene cluster in the fimbrial assembly and antigenic heterogeneity among fimA genotypes

K Nagano, Y Abiko, Y Yoshida, F Yoshimura - Journal of Oral Biosciences, 2012 - Elsevier
In order for bacteria to exert their pathogenicity, they must adhere to and colonize the host
tissues. Porphyromonas gingivalis, a periodontal pathogen, primarily exploits FimA fimbriae …

A Major Fimbrilin Variant of Mfa1 Fimbriae in Porphyromonas gingivalis

K Nagano, Y Hasegawa, Y Yoshida… - Journal of dental …, 2015 - journals.sagepub.com
The periodontal pathogen Porphyromonas gingivalis is known to express 2 distinct types of
fimbriae: FimA and Mfa1 fimbriae. However, we previously reported that fimbria-like …

Porphyromonas gingivalis FimA Fimbriae: Fimbrial Assembly by fimA Alone in the fim Gene Cluster and Differential Antigenicity among fimA Genotypes

K Nagano, Y Hasegawa, Y Abiko, Y Yoshida… - 2012 - journals.plos.org
The periodontal pathogen Porphyromonas gingivalis colonizes largely through FimA
fimbriae, composed of polymerized FimA encoded by fimA. fimA exists as a single copy …

Genetic and antigenic analyses of Porphyromonas gingivalis FimA fimbriae

K Nagano, Y Abiko, Y Yoshida… - Molecular oral …, 2013 - Wiley Online Library
The periodontal pathogen Porphyromonas gingivalis generally expresses two distinct
fimbriae, FimA and Mfa1, which play a role in biofilm formation. The fimA gene that encodes …

FimB Regulates FimA Fimbriation in Porphyromonas gingivalis

K Nagano, Y Hasegawa, Y Murakami… - Journal of dental …, 2010 - journals.sagepub.com
The periodontitis-associated pathogen Porphyromonas gingivalis colonizes and forms a
biofilm in gingival crevices through fimbriae. It is known that the often-used strains ATCC …

Role of Mfa5 in Expression of Mfa1 Fimbriae in Porphyromonas gingivalis

Y Hasegawa, Y Iijima, K Persson… - Journal of dental …, 2016 - journals.sagepub.com
Fimbriae are protein-based filamentous appendages that protrude from the bacterial cell
surface and facilitate host adhesion. Two types of fimbriae, FimA and Mfa1, of the …

Differential expression and adherence of Porphyromonas gingivalis FimA genotypes

C Zheng, J Wu, H Xie - Molecular oral microbiology, 2011 - Wiley Online Library
Porphyromonas gingivalis is a primary pathogen involved in the initiation and progression of
adult chronic periodontitis. Its colonization on oral surfaces is a necessary first step leading …

Localization and function of the accessory protein Mfa3 in Porphyromonas gingivalis Mfa1 fimbriae

Y Hasegawa, K Nagano, R Ikai… - Molecular oral …, 2013 - Wiley Online Library
The fimbriae of Porphyromonas gingivalis, the causative agent of periodontitis, have been
implicated in various aspects of pathogenicity, such as colonization, adhesion and …

Histidine Kinase-Mediated Production and Autoassembly of Porphyromonas gingivalis Fimbriae

K Nishikawa, MJ Duncan - Journal of bacteriology, 2010 - Am Soc Microbiol
Porphyromonas gingivalis, a Gram-negative oral anaerobe, is strongly associated with
chronic adult periodontitis, and it utilizes FimA fimbriae to persistently colonize and evade …