Antiviral activity and underlying mechanisms of baicalin against avian infectious bronchitis virus in vitro

H Feng, K Zhang, K Zhang, Z Guo, Q Liu, L Wang… - Avian …, 2022 - Taylor & Francis
Baicalin, a flavonoid compound extracted from the dry root of Scutellaria baicalensis Georgi,
has been shown to have anti-inflammation, anti-viral, anti-bacterial, and immunomodulatory …

Phillygenin activates PKR/eIF2α pathway and induces stress granule to exert anti-avian infectious bronchitis virus

H Feng, J Zhang, K Zhang, X Wang, K Zhang… - International …, 2022 - Elsevier
The prevalence of avian infectious bronchitis virus (IBV) is still one of causes inducing
severe losses of production in the poultry industry worldwide. Vaccination does not …

[HTML][HTML] Baicalin Protects Broilers against Avian Coronavirus Infection via Regulating Respiratory Tract Microbiota and Amino Acid Metabolism

H Feng, J Zhang, X Wang, Z Guo, L Wang… - International Journal of …, 2024 - mdpi.com
An increasing amount of evidence indicates that Baicalin (Bai, a natural glycosyloxyflavone
compound) exhibits an antiviral effect against avian viruses. However, it remains unclear if …

[HTML][HTML] Baicalin from Scutellaria baicalensis blocks respiratory syncytial virus (RSV) infection and reduces inflammatory cell infiltration and lung injury in mice

H Shi, K Ren, B Lv, W Zhang, Y Zhao, RX Tan, E Li - Scientific reports, 2016 - nature.com
The roots of Scutellaria baicalensis has been used as a remedy for inflammatory and
infective diseases for thousands of years. We evaluated the antiviral activity against …

Baicalin mitigates nephropathogenic infectious bronchitis virus infection-induced spleen injury via modulation of mitophagy and macrophage polarization in Hy-Line …

G Tian, C Huang, Z Li, Z Lu, C Feng, Y Zhuang… - Veterinary …, 2023 - Elsevier
Nephropathogenic infectious bronchitis virus (NIBV) infections continue to pose a significant
hazard in the poultry industry. Baicalin is a natural flavonoid that has been reported to have …

[HTML][HTML] Role of Baicalin in anti-influenza virus A as a potent inducer of IFN-gamma

M Chu, L Xu, M Zhang, Z Chu, Y Wang - BioMed research …, 2015 - hindawi.com
Baicalin (BA) is a flavonoid compound purified from Scutellaria baicalensis Georgi and has
been shown to possess a potent inhibitory activity against viruses. However, the role of BA in …

In vivo effect of quantified flavonoids-enriched extract of Scutellaria baicalensis root on acute lung injury induced by influenza A virus

HJ Zhi, HY Zhu, YY Zhang, Y Lu, H Li, DF Chen - Phytomedicine, 2019 - Elsevier
Background Scutellaria baicalensis root is traditionally used for the treatment of common
cold, fever and influenza. Flavonoids are the major chemical components of S. baicalensis …

[HTML][HTML] In vitro antiviral activity of fifteen plant extracts against avian infectious bronchitis virus

R Lelešius, A Karpovaitė, R Mickienė… - BMC veterinary …, 2019 - Springer
Background Avian infectious bronchitis (IB) is a disease that can result in huge economic
losses in the poultry industry. The high level of mutations of the IB virus (IBV) leads to the …

Antiviral activity of baicalin against influenza A (H1N1/H3N2) virus in cell culture and in mice and its inhibition of neuraminidase

Y Ding, J Dou, Z Teng, J Yu, T Wang, N Lu, H Wang… - Archives of …, 2014 - Springer
Abstract Scutellaria baicalensis Georgi, a Chinese herbal decoction, has been used for the
treatment of the common cold, fever and influenza virus infections. In previous studies, we …

[HTML][HTML] Inhibitory Effects of Belamcanda Extract on Inflammatory Response and Antiviral Mechanism in H9N2 Avian Influenza Virus: Insights from In Vitro and In Vivo …

Y Zhi, J Wei, Z Liu, Q Zhang, T Zhang, G Hu - Poultry Science, 2024 - Elsevier
Avian influenza, particularly the H9N2 subtype, presents significant challenges to poultry
health, underscoring the need for effective antiviral interventions. This study explores the …